布-加综合征与抗凝治疗.PDFVIP

中华普通外科学文献 （电子版） 2018 年 月第 卷第 期 （ ） 10 12 5 Chin Arch Gen Surg Electronic Edition , October 2018, Vol. 12, No.5 • • 363 ·综述 · 布- 加综合征与抗凝治疗 李素新  李路豪  党晓卫 【摘要】布- 加综合征（B-CS ）是严重威胁人类健康的一种肝后型门静脉高压症，世界各地发 病不一。随着对B-CS 基础和临床研究的深入，其病因、病理生理以及临床治疗均取得了很大的进展。 一直以来，由于地域和病因差别较大，国内外对B-CS 凝血功能及抗凝治疗的观点莫衷一是。本文 就近年来国内外关于B-CS 与抗凝治疗的现状和进展作一综述。 【关键词】 Budd-Chiari 综合征；抗凝治疗；并发症；肝纤维化 Budd-Chiari syndrome and anticoagulation therapy Li Suxin, Li Luhao, Dang Xiaowei. Department of Hepatobiliary Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China Corresponding author: Dang Xiaowei, Email: dangxw1001@163.com Abstract 【 】 Budd-Chiari syndrome (B-CS) is a kind of post-hepatic portal hypertension, which is threatening human health and occurs differently in epidemiology. With the development of basic and clinical research of B-CS, its etiology, pathophysiology and clinical therapeutics have been achieved great progress. Because of the differences of geography and etiology, the coagulation and anticoagulation therapy on B-CS are controversial both at home and abroad all the time. In this paper, the current status of anticoagulation therapy on B-CS in recent years is reviewed. Key words 【 】 Budd-Chiari syndrome; Anticoagulation; Complication; Hepatic fibrosis 广义的布- 加综合征（Budd-Chiari syndrome, 成危险因素，主要的病因是骨髓增生异常性疾病 ［2］ B-CS ）是指肝静脉流出道受阻伴或不伴下腔静脉 （myeloproliferative neoplasms, MPN