酮咯酸氨丁三醇肌内注射超前镇痛联合喷他佐辛自控静脉镇痛在外科全身麻醉手术后镇痛中的效果及可行性分析.docVIP

酮咯酸氨丁三醇肌内注射超前镇痛联合喷他佐辛自控静脉镇痛在外科全身麻醉手术后镇痛中的效果及可行性分析 　　[摘要]目的 探?酮咯酸氨丁三醇肌内注射超前镇痛联合喷他佐辛自控静脉镇痛（PCIA）在外科全身麻醉（全麻）手术后镇痛中的效果及可行性。方法 根据随机数字表从2015年8月～2017年5月在我院外科实施全麻手术治疗的患者中选取185例作为研究对象并采用抽签方法分组，其中接受单药镇痛的设为对照组，接受酮咯酸氨丁三醇肌内注射超前镇痛联合喷他佐辛PCIA的设为试验组，比较两组术后不同时间点的镇痛效果。结果 与对照组比较，试验组患者在术后不同时间点的视觉模拟评分明显降低，且试验组术后8 h内各时间点的PCIA次数显著减少，两组比较差异有统计学意义（P0.05）。结论 外科全身麻醉患者应用酮咯酸氨丁三醇肌内注射超前镇痛联合喷他佐辛PCIA，有助于减轻术后疼痛程度，安全可靠，值得临床推广应用。 　　[关键词]酮咯酸氨丁三醇；喷他佐辛；超前镇痛；自控静脉镇痛；全身麻醉；疗效 　　[中图分类号] R614.2+2 [文献标识码] A [文章编号] 1674-4721（2017）09（b）-0111-03 　　Effect and feasibility analysis of intramuscular injection of Ketorolac Tromethamine for preemptive analgesia combined with Pentazocine for patient controlled intravenous analgesia after general anesthesia surgery in surgery department 　　LIU Ai-hua ZHANG Hui-min YIN Fang TIAN Li-chuan XU Qian WANG Yue-xin 　　Department of Anesthesiology，Medical College Campus of Cangzhou People′s Hospital in Hebei Province，Cangzhou 061000，China 　　[Abstract]Objective To investigate the effect and feasibility of Ketorolac Tromethamine for preemptive analgesia combined with Pentazocine for patient controlled intravenous analgesia （PCIA） after general anesthesia surgery in surgery department.Methods 185 patients were selected from August 2015 to May 2017 according the random number table method among the patients given general anesthesia in surgery department of our hospital and they were grouped by drawing lottery.Participants provided with single drug for analgesia were classified into control group，while intramuscular injection of Ketorolac Tromethamine for preemptive analgesia combined with Pentazocine for PCIA was categorized into experimental group.The analgesic effect at different time points after surgery were compared between the two groups.Results Compared with control group，visual analogue scale at different time points after surgery in the experimental group were significantly lower than those in control group.Besides，frequency of PCIA at differ time points within 8 hours a