前列地尔联合血塞通治疗房颤合并后循环缺血眩晕临床的研究.docVIP

前列地尔联合血塞通治疗房颤合并后循环缺血眩晕临床的研究 　　[摘要] 目的 探究前列地尔联合血塞通在治疗房颤合并后循环缺血眩晕中的治疗效果。 方法 方便选取2013年2月―2015年9月期间该院收治的90例房颤合并后循环缺血眩晕患者，将所有患者随机分为两组，各45例。对照组采用血塞通治疗，观察组在血塞通治疗的基础上加用前列地尔治疗，分析比较两组治疗效果。 结果 治疗后，观察组血流速度高于对照组，差异有统计学意义（P0.05）；治疗第3天，观察组患者眩晕症状评分为（33.1±10.2）分低于对照组（48.7±11.6）分，治疗第7天，观察组眩晕症状评分为（22.3±12.4）分，显著低于对照组（38.9±13.4）分，差异有统计学意义（P0.05）。结论 前列地尔联合血塞通在治疗房颤合并后循环缺血眩晕中临床效果显著，改善血流动力学，提高患者的生活质量，在临床应用中具有推广价值。 　　[关键词] 前列地尔；血塞通；房颤合并后循环缺血眩晕 　　[中图分类号] R743 [文献标识码] A [文章编号] 1674-0742（2016）09（c）-0148-03 　　[Abstract] Objective To investigate the curative effects of alprostadil combined with xuesaitong in the treatment of atrial fibrillation（AF） and posterior circulation ischemia vertigo（PCIV）. Methods Convenient select February 2013 to September 2015 90 cases admitted during circulation ischemia vertigo in patients with atrial fibrillation， 45 cases in each. Control group was treated with xuesaitong and observation group was treated with alprostadil on the basis of xuesaitong. The curative effects of two groups were compared and analyzed. Results After treatment， blood flow velocity of observation group was statistically higher than that of control group，the difference was significant（P0.05）； Treatment of the first 3d， the observation group were dizziness symptom scores （33.1 ± 10.2）point than the control group （48.7 ± 11.6）point， the first treatment 7d， the observation group vertigo symptom scores （22.3 ± 12.4）point， significantly lower than the control group （38.9 ± 13.4）point， the difference was significant （P 0.05）. Conclusion Alprostadil combined with xuesaitong in the treatment of AF and PCIV has significant clinical efficacy， and it can improve hemodynamics and increase patients’ living quality， which is worthy of generalization in clinical application. 　　[Key words] Alprostadil； Xuesaitong； Atrial fibrillation and posterior circulation ischemia vertigo 　　后循环缺血主要是由于动脉出现粥样硬化、椎基底动脉供血不足等因素造成[1]。若得不到及时的治疗，极易引发血栓等心脑血管疾病，危及生命[2]。房颤属于最常见的心律失常，研究调查显示[3]，随着年龄的增长，房颤合并后循环缺血眩晕发病率逐渐升高。该研究方便