儿童白血病介绍(自制)医学演示课件.pptVIP

. . Biphenotypic acute leukemia is defined when scores are 2 for the myeloid lineage and 1 for the lymphoid lineage. . 染色体及基因 . Subtype Associated Features Hyperdiploidy (50 chromosomes) Predominant B cell precursor phenotype; low leukocyte count; favorable age group (1–9 years) and prognosis in children Hypodiploidy (45 chromosomes) Predominant B cell precursor phenotype; increased leukocyte count; poor prognosis TEL-AML1 fusion? CD13±/CD33± B cell precursor phenotype; pseudodiploidy; age 1–9 years; favorable prognosis t(1;19)(q23;p13.3) with E2A-PBX1 fusion? CD10±/CD20–/CD34– pre-B phenoty