遗传学课件monogenic diseasea教学材料.ppt

Monogenic Disease;The pedigree is a visual tool for documenting biological relationships in families and the presence of traits or diseases.;1. Pedigree;;I II;Information of family members more than three generations Information verified by genetic consultant Investigating the death cause, death age, consanguineous marriage, fetal death, abortion, neonatal death;AD inheritance are those in which a single copy of a mutant gene on autosome is enough for the trait to be expressed or shown.;The phenotype of the heterozygote (Aa) will be indistinguishable from the phenotype of the homozygous (AA) d