遗传工程小鼠的制备繁育及应用教学幻灯片.pptxVIP

遗传工程小鼠的制备繁育及应用;第一个转基因小鼠（1982）;The “conventional” transgenesis is using short constructs with well-defined promoter regions.?;基因组改造技术是建立疾病模型的核心;;;出生后心脏发育不良和心衰;Fstl1, Follistatin-like 1;nervous system;Lung Development;Ureter Development;The CRISPR Craze A bacterial immune system yields a potentially revolutionary genome-editing technique;CREDIT: K. SUTLIFF/SCIENCE;Cas9技术流程;2;One-Stop Services ;The first cKO mouse in china(2005) The first single and multiple genes Cas9 KO mouse in china(2013) The first Cas9 cKO rat in china(2013) The first KO monkey in the world (2015) The first KO dog in the w