不同年龄段变应性疾病患者变应原检测剖析.docVIP

不同年龄段变应性疾病患者变应原检测剖析 　　摘要：目的 采用体外血清学检测方法检测变应性疾病患者的变应原，并按年龄段分组进行比较分析。方法 对2012年7月~11月我院门诊就诊的变态反应患者共535例，采用德国Mediwess公司生产的Allergy Screen系统进行变应原的slgE血清学检测。结果 ①儿童组变应原检出阳性率为73.14%，高于其他各年龄段；②不同年龄段的变应原分布有差异，吸入性变应原中，slgE阳性率最高者为户尘螨，占78.5%；儿童组户尘螨lgE阳性率又高于其他各年龄段，为89.74%；③对吸入性变应原，户尘螨组及猫狗皮屑组不同年龄段的slgE的检测值有明显差异[1]，对户尘螨slgE的检测值，儿童组与其他各年龄段的差异最为明显（t=2.018, 3.174, 3.476；P=0.045，0.002, 0.001）。结论 不同变应原检测阳性率及其与总体阳性率随年龄变化的分布趋势不完全一致。同时slgE的检测值，儿童组与其余各组的差异也最大。建议对儿童的变应性疾病应早期进行干预。 　　关键词：AllergyScreen检测系统；变应原；变应性疾病 　　Analysis of Different Ages in Patients with Allergic Diseases Allergen Detection 　　WEI Jun 　　(Department of Otolaryngology Head and Neck Surgery,Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200062,China) 　　Abstract：ObjectiveAllergen detection in ptients with allergic disease using serologicl detection method,analzing and comparing by age group.MethodsForpatients in our hospital during November 2012 to July a total 535 allergic reaction,slgE serological detection of allergen by AllergyScreen system manufactured by Mediwess company in Germnay. Results①Children allergen positive rate was 73.14%,higher than the other age.②Distributions of allergens of different ages have different,inhaled allergens,the positive rate of slgE was highest in Dermatophagoides pteronyssinus 78.5%,children dermatophagoides pteronyssinus lgE positive rate was higher than the other age groups,89.74%.③For inhalation allergen detection of different ages, the values of slgE are significantly different for house dust mite and cat dog dander group,detection of house dust mite slgE values,different groups of children and other age is the most obvious（t=2.018, 3.174, 3.476；P=0.045，0.002, 0.001）.For food allergens in children group for milk,and the other three groups were significnt differences（t=2.163, 2.338, 2.370, p=0.026,0.021,0.02）.ConclusionDistribution of positive rate in different allergens and the positive rate of the overall change with age is not consisten