从针刺不同经穴对家兔胃黏膜保护作用探讨多经司控同一脏腑的规律.PDF

中国针灸 2004年 8月第24卷第 8期 · 579 · 文章编号：0255—2930(2004)08—0579 04 讨 ： 中图分类号：R245．9 文献标识码：A + + + - 从针刺不同经穴对家兔胃黏膜保护作用探讨 多经司控同一脏腑的规律 严 洁 阳仁达 易受乡 常小荣 林亚平 (湖南中医学院针灸推拿系，长沙 410007) [摘 要] 目的：探讨经脉腧穴与脏腑的特异关系。方法：将 56只家兔随机分为7组，分别针刺不同 经的穴位。硝酸还原酶法测定胃黏膜 NO和NOS含量，放射免疫法测定PGE2、EGF含量，加权法 分析各组综合效应。结果：(1)针刺足阳明经组与其余各组比较，能显著升高胃黏膜PGE。、EGF含 量(PO．O1)；(2)针刺足阳明、足太阴经组与其余各组比较，能显著升高胃黏膜NO和NOS含量 (P0．O1)；(3)针刺足阳明经组综合效应明显高于其余各组(P0．O1)；针刺足太阴经组综合效 应明显高于模型组(P(O．O1)。结论：多经司控同一脏腑具有一定的普遍性，但从作用强度和广度 看又具有经脉的相对特异性；胃与足阳明经关系最为密切，足太阴经次之。 [主题词] 脏腑经络关系；胃黏膜／针灸效应 Study on regularity of multi··meridians controlling a same organ from the protective action of acu·· puncture at different acupoints on gastric mucosa in the rabbit YANJie， 4 『GRen—da，YIShou—xiang，et a1．(Acupuncture-Moxibustion andMassageDepartment，HunanCol- 1ege of TCM，Changsha 410007，China) ABSTRACT Objective To probe the special relation between the acupoint with zang—and —organs．Methods Fifty—six rabbits were randomly divided into 7 groups．which were treated respectively by acupuncture at acupoints of different channels．Nitric oxide(N0)level and nitric oxide synthase(NOS)activity in gastric mucosa were deter— mined by the nitric acid reductase method，and prostaglandin E2(PGE2)and epidermal growth factor(EGF)levels were measured by radioimmunoassay．The comprehensive effects were analyzed by weighting method．Results (1) The levels of PGE2 and EGF in the gastric mucosa in the group treated by acupuncture at the Foot-Yangming Merid— ian increased．significantly a