磁性高分子复合微球的制备及表面改性-凝聚态物理专业论文.docx

华中科技大学硕士学位论文 华 中 科 技 大 学 硕 士 学 位 论 文 II II Abstract Magnetic polymer composite microspheres are combined with inorganic magnetic particle and organic polymer materials through a certain way. They not only has the excellent magnetic property of inorganic magnetic particles, but also have the function of organic polymer materials, such as functional group properties and biocompatibility. Then we can link different kinds of abundant active functional groups into the surface of magnetic microspheres. Because above advantage, they have very important application prospect in biotechnology and biomedical fields, such as cell separation, targeted drug, immobilized enzyme and immune detection. In this study, we prepared magnetic polymer composite microspheres, which have many shell structure , by improved dispersion polymerization. Then we connected –NH2 groups successfully on its surface by the way of surface modification, at the same time, using PEG solution to change –NH2 into –COOH, made the surface of magnetic microspheres realized carboxylation. In our experiment process, optical microscopy and scanning electron microscopy (SEM) are used to observe morphology and size distribution characteristics of microspheres; Thermal gravity analysis (TGA) is used to measure the component content and hot stability of microspheres; Vibrating sample magnetometer (VSM) is used to measure the magnetic property of microspheres; Fourier transform infrared spectrometer (FTIR) and conductometric titration are used to analyze the composition and content of functional group (-NH2,-COOH) ,which are on the surface of microspheres. Key words: Magnetic polymer composite microspheres Dispersion polymerization Amino group carboxyl group PAGE IV PAGE IV 目 录 摘 要 I Abstract II 1 绪论 1.1 磁性高分子复合微球概述 (1) 1.2 本文工作 (6) 2 超顺磁性 Fe3O4 纳米颗粒的制备及表面改性 2.1 高温热分解法制备 Fe3O4 纳米颗粒及表面改性 (8) 2.2 测试超顺磁性 Fe3O4 纳米颗粒的性能及结果分析 (11) 2.3 本章小结 (14) 3 Stober 法制备二氧化硅微球 3.1 实验的理论基础 (15) 3.2 二氧化硅微球的制备 (16) 3.3 测试二氧化硅微球的性能及结果分