中药丸剂干燥工艺.pdf

中草药 Chinese Traditional and Herbal Drugs 第 47 卷 第 13 期 2016 年 7 月 ·2365 · ·综 述· 中药丸剂干燥工艺、装备应用现状及问题分析 * * 王学成，伍振峰 ，王雅琪，杨 明 江西中医药大学 现代中药制剂教育部重点实验室，江西 南昌 330004 摘 要：干燥是中药丸剂制剂工艺流程中的一个重要环节，而干燥方法的选择和工艺参数优化直接决定了中药丸剂干燥成品 质量。综述了工业应用较成熟的传统丸剂干燥方式如厢式热风干燥、真空干燥及箱式微波干燥的原理及技术特点，以及一些 新型丸剂干燥技术及设备的应用前景。中药丸剂干燥仍存在工艺方法选择局限、干燥设备智能化程度不高及设备适宜性不良 等问题，需通过深入研究丸剂干燥机制、融合精确传感的新技术及计算机智能控制技术实现中药丸剂干燥设备智能化及符合 GMP 生产要求。 关键词：中药丸剂；干燥技术；智能化；GMP ；厢式热风干燥；真空干燥；箱式微波干燥 中图分类号：R283.3 文献标志码：A 文章编号：0253 - 2670(2016)13 - 2365 - 08 DOI: 10.7501/j.issn.0253-2670.2016.13.027 Analysis on drying process, equipment application status and problem of Chinese materia medica pills WANG Xue-cheng, WU Zhen-feng, WANG Ya-qi, YANG Ming Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China Abstract: The drying technology is one important part in the preparation process of Chinese materia medica pills. However, the quality of dried CMM pills is directly determined by selection of drying method and optimization of process parameters. The paper summarized the principle and technical feature of drying methods for CMM pills which were widely used in industry, such as hot air box drying, vacuum drying, and microwave box drying. The application prospect of some new drying technology for CMM pill as well as equipment was introduced. Problems of limited selection of drying process, low degree intelligent drying equipment, and poor adaptability of equipment existed on drying process of CMM pills. The drying equipment of CMM pills will meet the requirement of GMP production and be more intelligent by in-depth studying on drying mechanism, fusion of new technology on precise sensing, and com