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sci 论文常用句型摘抄 1. Taken together,our dataprovidenew mechanistic insightsintopossibleendogenous signaling metastatic signaling pathways involved in maintaining proliferation and migration of breast cancer cells. 2. We sought to determine whether seliciclib (CYC202, R-roscovitine) could increase the antitumor effects of doxorubicin, with no increase in toxicity, in an MCF7 breast cancer xenograft model. 3. MIB1(ki67) immunohistochemistry demonstratedreducedproliferation with treatment.(用于 ki67方面) 4. Survivin embodiestheseproperties,and 5. Moreover, in pre-clinical bladder tumor models, inhibition of Survivin expression and/or function has been shown to impede tumor cell proliferation, and markedly induce spontaneousor chemotherapy inducedapoptosis 6. The efficacy of mainstay cancer therapies, cytotoxics and radiation, has reached a plateau in the treatment of many cancers, and there is an urgent sense that improvements must now come from fresh approaches. 7. Median agewas62yearswith arangeof40-74years. 8. splice variants might function in effect as dominant negatives so that their expression might concurrentwith survivin. 9. Thereisahypothesisthat 10. The absence of in vivo data on thispoint hasnow been remediedwith apaper in thisissue of theJCIbyAltieri andcolleagues. 11. Thus,thisraisesan interesting questionwhether... 12. raisingthepossibility thatmost,ifnot all,tumorsexpress... 13. The levels ofp21andp27 increased after treatment with doxorubicin or seliciclib alone or in combination,comparedtountreatedcontrols. 14. In contrast,it isabundantly expressedin awidevariety ofmalignanttissues. 15. On thecontrary,... 16. By contrast, a good title will attract the relevant researchers and increase the number of citationsyou receive 17. Wehave foundthat the human breast cancer cells MCF-7/Adr overexpressnot only P-gp but also XIAP