大豆异黄酮的抗氧化和抗肿瘤活性研究.pdfVIP

29 5 Vol. 29 N o. 5 2010 10 SOYBEAN SCIENCE Oct. 2010 1 2 3 徐春华 , 张治广, 谢明杰 ( 1. , 116037; 2. , , 116029; 3. , 116029) : enton, , MTT CBRH-7919 CML-K562 : - 1 50% ( IC ) 0. 14 m g# mL ; 50% 50 - 1 ( IC ) 0. 57 m g# mL ; CBRH-7919 50% ( IC ) 7. 55 mg 50 50 - 1 - 1 # L ; CML-K562 50% ( IC ) 10. 35 mg# L 50 : ; ; : T730. 1 : A : 1000- 9841(2010) 05- 0870- 04 Research onAntioxygenic andAntitumorActivities of Soybean Isoflavones 1 2 3 XU Chun-hua, ZHANG Zhi-guang, X IE M ing-jie ( 1. Electrical and Electronic Eng ineering Technology Departm ent, Dalian Vocational and TechnicalCollege, Da lian 116037; 2. College of Chem istry and Chem ical Eng ineering, Liaoning N orm alUniversity, Dalian 116029; 3. The College ofL ife Science, L iaoningN orm alUniversity, Dalian 116029, L iaon- ing, China) Abstract: To investigate the b ioligical activities of soybean isoflavones, pyrogallol autoxidation m ethod and enton m ethod w ere used to detectw hether soybean isoflavones cou ld scaverge hydroxyl free radical and superoxide free rad ical. MTT assay w as used to exam ine the effect of soybean isoflavoneson cellviabilities. The results showed that soybean isoflavones exhib ited antioxygenic activities, the antitum or and antibacterial activities 50% elmi ination concentration of soybean i