降脂红曲微粉对高脂血症临床疗效的对比研究-中西医结合临床专业论文.docxVIP

y y SOIl67 提要 目的：观察不同剂照降脂缒曲微粉对商脂j缸症的临床疗效和安全性，为降脂红曲 的貉床应用和歹l：发提供辩学裱摄。方法：s0铡舞疆盘痰蠹嚣戆爨分为4令组，A缓 (降腊纨曲微粉1／2剂辍组)，B组(降脂红曲微粉组)，C组(降脂红曲粗粉组)和 D组(髓脂康缀)。观察治疗前籍临床瘫狡、舷脂与抗戴纯、巍管蠢疫势泌功§￡及驻 动脉内皮依赖憾舒张功能等指标变化。f结果：4组用药50天届，临床瘢状均明疑改 L 菩，A、B两缎临床症状总疗效的显效率及乏力症状改善的总脊效率明驻优于C、D 媾组。务缓虫滤总疆固辩{#拳鼹著降低，其毽蜜验室攒振办有不囤程发的改善：A、 D两组降脂总有效率显著优于C组；A组甘油曼酯含量显著降低。降钙綮基因相关肽 鼗著嚣辩； A、蛰两缀稼动蠢|；：肉皮蒎赣毪舒张葫链显蕊改善，内疫素，瓣钙素鏊因粳 关肽显蔫降低，后4项指标其他组未见照著改变。辫论；降脂红曲微粉降脂与缓解临 床症状疗效肯寇，安全有效，强其有抗氯亿，傈护盎管肉皮等俸用，裁熬胃瓯较常褒 粉碎者减半，慎德推广成用。 关键裁黪艚红麴；孛药微耪；毫麟盘瘥；内壤功熊；浆露研究} Comparative Comparative Study of CI inicaI Effect on Treatment of HyperI ipemia with Micro—powder of LiPid—reducing Hongqu SpeciaI ity：InternaI MadiCine of Integrated TOM and Western MediCiRe Author：LiU Longtao Tutor：Zhang wengao Abstract Objective：To observe the therapeutiC effect and security on treatment of hyperlipemia with different doses of micro—powder of lipid—reducing Hongqu(MLH)，and provide scientific proof for its clinical application and development．Methods：80 cases of hyperlipemia patients were divided randomly into 4 groups：21 cases in Group A(MLH of 1／2 dose group)。20 cases in Group B(MLH of full dose group)，19 cases in Group C(rough—powder of Iipid—reducing Hongqu group)and 20 cases in group D(Xuezhikang group)．To observe the changes of clinical symptoms，blood 1ipid，anti—oxidation，secretion function of vascular endothelium and endothelium-dependent relaxing function of brachial artery．Results：After 50 days of treatment．clinical symptoms improved in all groups，and the significant effective rate and total effectire rate to tiredness of h and B groups were superior to those of C and D groups．TC in a1 l groups．reduced remarkabiy．and other laboratory indexes improved with different extent in each group．Total effective rate of A and B groups in reducing lipid was superior to that of C group．TG reduced and CGRP elevated in group A．Endothel ium—dependent diastol ic function of brachial artery improved and ET／CGRPreduced in A and D groups．Conclusion：MLH had such m