金属配位型分子印迹聚合物催化剂的制备及其催化作用研究-有机化学专业论文.docxVIP

(2)利用Fe(III)的配位作用在分子印迹聚合物制备过程中的优势，以 (2)利用Fe(III)的配位作用在分子印迹聚合物制备过程中的优势，以 FeCl3与对硝基苯甲醇的配合物为模板，丙烯酰胺为功能单体，制备分子印 迹催化剂Fe(III)．MIP；通过研究该催化剂对不同醇类氧化反应的催化活性， 表f1)jFe(III)．MIP催化剂在不同取代基的苯甲醇氧化反应中，表现出相对于非 印迹聚合物催化齐ljFe(III)．NIP更高的催化活性，且对模板分子一对硝基苯甲 醇具有专一的底物选择识别性。 (3)以氯金酸与对硝基苯甲醇的配合物为模板，丙烯酰胺为功能单体， 制备了含有纳米金粒子的Au．MIP分子印迹催化剂。分别考察了该催化剂在 邻，间，对一硝基苯甲醇的氧化反应的催化活性。结果表明Au．MIP具有与 对硝基苯甲醇结构完全匹配的印迹结构和可高效识别对硝基苯甲醇的识别 位点，因此对模板分子底物一对硝基苯甲醇显示出专一的底物选择识别性； 在不同取代基的苯甲醇氧化反应中，Au．MIP对具有可与印迹结构中识别位 点结合的取代苯甲醇表现出更高的识别性。 关键词：分子印迹催化剂，金属配位，底物识别性，选择性，傅克酰基化 反应，苯甲醇氧化反应 lI ABSTRACTWith ABSTRACT With the predetermination，specificity，stability and practicability,molecularly imprinted polymer(MIP)has been attracted much attentions in the recent years． It has been mainly applied in the fileds of the chromatographic separation，solid extraction，clinical drug analysis，sensor technology and SO on．However，less afford of MIP has been made on organic catalysis，except for the hydrolysis reaction．The hydrolysis catalysts made of MIP contained the recognition sites and the imprinted cavities，which could stabilize the transition state or selecte a specific product in the catalytic process．The introduction of the catalytic active sites into the imprinted cavities may provide the efficient catalysis performances and specificity．With this points in mind，designed and prepared molecular imprinting catalyst containing catalytic active sites might provide a means to develop high efficient catalysts with specificity． In this thesis，a kind of molecular imprinting catalysts based on the self-assembly of template and metal ion have been prepared and applied in the fine organic synthesis．Related informations indicated that the activity and specificity of the catalyst was dramatically improved and an imprint of a higher fidelity． (1)The Co(II)-MP was prepared by the molecular imprinting of a complex between 2-acetylcyclohexanone and cobalt(II)ion in a 4-vinylpyridine·-styrene·· III divinylbenzene divinylbenzene copolymer．This polymer was well char