血栓前状态与不良妊娠关系的研究进展.pdfVIP

中国医药导报 年 月第 卷第 期 2015 8 12 24 ·综 述 · 血栓前状态与不良妊娠关系的研究进展 谢振荣 林思瑶 沈柏儒 梁 娇 杨成刚 甄曼华 张映辉 广东省佛山市禅城区中心医院 广东医学院附属佛山禅城医院妇产科，广东佛山 528000 摘要 血栓前状态是指因血液系统持续高血凝状态而导致的机体处于易栓状态，是血管内皮细胞、血小板、凝血 [ ] 系统、抗凝系统、纤溶系统以及血液流变学等多种因素综合作用下发生的凝血和抗凝系统失调的一种病理过程， 同时也是机体过渡为血栓病理状态的病理过程。 研究血栓前状态的病理生理过程，是预防血栓性疾病的重要基 础。 许多妊娠不良结局的妇女均具有血栓形成倾向，抗凝治疗被公认为对于血栓前状态有效的治疗方法。 因此研 究血栓前状态与不良妊娠结局的关系有利于其尽早进行治疗和预防。 关键词 血栓前状态；不良妊娠；抗凝治疗 [ ] 中图分类号 文献标识码 文章编号 （ ） （ ） [ ] R714.51 [ ] A [ ] 1673-7210 2015 08 c -0053-05 Research progress of the relationship between the pre -thrombosis state and the adverse pregnancy XIE Zhenrong LIN Siyao SHEN Bairu LIANG Jiao YANG Chenggang ZHEN Manhua ZHANG Yinghui Department of Obstetrics and Gynecology, Chancheng District Central Hospital of Foshan City Affiliated Chancheng Hospital of Guangdong Medical College, Guangdong Province, Foshan 528000, China [Abstract] Pre-thrombosis state (PTS) is the thrombosis caused by persistent high blood coagulation state, and a patho- logical process of hemostasis, coagulation and anticoagulation system disorders affected by vascular endothelial cells, platelet, coagulation, anticoagulant, fibrinolysis system and blood rheology and other factors. Many women with adverse pregnancy outcomes have the tendency of thrombosis, and anticoagulant therapy is regarded as an effective method for the treatment of PTS. So the study of the relationship between PTS and adverse pregnancy outcomes is in favor of the early treatment and prevention for thrombosis. [Key wo