腹主动脉旁淋巴结清扫治疗早期子宫内膜癌的疗效评价.docxVIP

腹主动脉旁淋巴结清扫治疗早期子宫内 膜癌的疗效评价 西电集团医院 摘要： 口的探讨腹主动脉旁淋巴结清扫治疗早期子宫内膜癌的疗效及安全性。方法选 取早期子宫内膜癌患者62例作为研究对象进行回顾性分析。根据淋巴结清扫范 围的不同将其分为A组(盆腔淋巴结清扫)及B组(盆腔淋巴结清扫+腹主动脉 旁淋巴结清扫)。比较2组患者手术情况、性激素水平、复发转移率及1年生存 率、并发症发生情况。结果B组患者手术吋间长于A组，淋巴结清扫数量多于A 组(P0. 05)，但2组术屮出血量及住院时间无统计学差异(P0. 05)。2组手 术前孕激素及雌激素水平均无统计学差异(P0.05);手术后2组孕激素水平明 显上升，雌激素水平明显下降，以B组变化幅度更为显著(P0. 05) °A组患者 复发转移率明显高于B组(P0. 05) ;B组患者1年牛存率略高于A组，但组间 差异不明显(P0. 05)。A组患者并发症发生率低于B组，但差异不明显 (P0. 05)。结论腹主动脉旁淋巴结清扫有利于淋巴结全面清扫，可刺激性激素 水平改善，能有效降低早期子宫内膜癌患者复发转移率，安全性尚可。 关键词： 早期了宫内膜癌;盆腔淋巴结清扫;腹主动脉旁淋巴结清扫;性激素; 收稿日期:2017-04-06 Efficacy of Periaortic Lymph Node Dissection in the Treatment of Early Endometrial Cancer ZHANG Xiuling Xian XD Group Hospital: Abstract： Objective To investigate the efficacy and safety of periaortic lymph node dissection in the treatment of early endometrial cancer. Methods A total of 62 patients with early endometrial cancer were retrospectively analyzed. According to the style of lymph node dissection， they were divided into group A ( pelvic lymph node dissection) and group B ( pelvic lymph node dissection + periaortic lymph node dissection) ? The operative condition, expression levelof sex hormone, recurrence and metastasis rate, 1-year survival rate and complicat ion rate were compared between the 2 groups. Results The opera tion time of group B was Ion ger than that of group A, and the number of lymph node dissection was higher than that of group A ( P 0. 05) , but there was no significant difference between the 2 groups ( P 0. 05) ? There was no significant difference in progesterone and estrogen levels between the 2 groups before operation ( P 0. 05). The expression levels of progesterone increased significantly and the estrogen level decreased significantly after operation, and the change of group B was more significant ( P〈 0. 05) . The recurrence and metastasis rate of group A was significantly higher than that of group B ( P 0. 05) ? 1-year survival rate of group B was slightly higher than that of group A, but the differen