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血管性死亡, 非致死性卒中 或非致死性心梗 P=0.52 Lancet. 2011 Feb 26;377(9767):741-50 Functional status at 6m OR 1.17,1.00–1.38; p=0.048 Lancet. 2011 Feb 26;377(9767):741-50 Secondary events during 6m Lancet. 2011 Feb 26;377(9767):741-50 目前为止卒中急性降压meta分析 总结 急性卒中后高血压反应非常常见 急性卒中后降压治疗存在争议 越来越多的研究倾向于卒中急性期给予降压治疗是安全的 谢谢 * Of the 563 704 patients with acute stroke (≥20 years of age) who enrolled in the US National Hospital Ambulatory Care Survey,9 390 584 (69.3%) had systolic hypertension (≥140 mm Hg), 172 186 (30?5%) had diastolic hypertension (≥90 mm Hg), and 235 843 (41?8%) had a mean arterial pressure of 107 mm Hg or higher. Systolic and mean arterial pressure were increased in all 4245 patients with subarachnoid haemorrhage.9 * International Stroke Trial 17398 patients Chinese Acute Stroke Trial, 15 888 (75?3%) patients * Systematic Review 32 studies included 10892 patients High Blood Pressure in Acute Stroke and Subsequent Outcome A Systematic Review Mark Willmot, Jo Leonardi-Bee, Philip M.W. Bath Abstract—High blood pressure (BP) is common in acute stroke and might be associated with a poor outcome, although observational studies have given varying results. In a systematic review, articles were sought that reported both admission BP and outcome (death, death or dependency, death or deterioration, stroke recurrence, and hematoma expansion) in acute stroke. Data were analyzed by the Cochrane Review Manager software and are given as odds ratios (ORs) or weighted mean differences (WMDs) with 95% confidence intervals (CIs). Altogether, 32 studies were identified involving 10 892 patients. When all data were included, death was significantly associated with an elevated mean arterial BP ([MABP] OR, 1.61; 95% CI, 1.12 to 2.31) and a high diastolic BP ([DBP] OR, 1.71; 95% CI, 1.33 to 2.48). Combined death or dependency was associated with high systolic BP ([SBP] OR, 2.69; 95% CI, 1.13 to 6.40) and DBP (OR, 4.68; 95% CI, 1.87 to 11.70) in primary intracerebral hemorrhage (PICH). Similarly,
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