口服莪术油抑制雌性棕色田鼠性行为和雌二醇受体在大脑核团中的表达.PDFVIP

兽类学报,2010,30 (2):218 - 222 Acta Theriologica Sinica 口服莪术油抑制雌性棕色田鼠性行为和 雌二醇受体在大脑核团中的表达  何凤琴 王波 (西安文理学院生命科学系, 西安 710065 ) 关键词:棕色田鼠;卵巢;莪术葡萄糖注射液;雌激素 α 受体 (ERα);混合饵料 中图分类号:Q42 文献标识码:A 文章编号:1000 - 1050 (2010)02 - 0218 - 05 Oral zedoary oil inhibited sexual behavior and the expression of estradiol receptor in brain nuclei of female mandarin vole (Microtus mandarinus)  HE Fengqin ,WANG Bo (Xi ’ an University of Arts and Science ,Xi ’ an 710065 ,China) Abstract :In order to investigate the effect of zedoary glucose injection on reproductive behavior in female mandarin voles (Microtus mandarinus),behavior focal sampling and immunohistochemistry methods were used to examine the relationships between behavior changes of female mandarin voles and estrogen receptor α immunoreactive neurons (ERα-IRs)in the ova- ry and in relevant brain regions after being fed with rabbit chow that was mixed with concentrations of 30 mg/ kg zedoary glucose injection. Healthy adult female voles were divided into experimental and control groups. The experimental group was fed with the mixed chow and carrot,and control group was fed with rabbit chow and carrot. Behaviors of the adult fe- male voles were observed after being fed for 30 days. The numbers of litters of these adult female voles after mating with a- dult male voles was recorded,and meanwhile the number of ERα-IRs in the relevant brain regions was detected. The re- sults showed that :during the period of intraspecies female-male interactions in a cage,the female voles in the experimental group displayed more escape behaviors,defensive behaviors,and hostile attacks than