冠脉病变与冠心病中医证型的相关性及蛭龙活血通瘀胶囊对气虚痰瘀型冠心病患者血管内皮功能的影响-中西医结合临床专业论文.docxVIP

西南医科大学硕士学位论文6-Keto．PGFla差异无统计学意义(尸0．05)，治疗后两组的 西南医科大学硕士学位论文 6-Keto．PGFla差异无统计学意义(尸0．05)，治疗后两组的 NO，6-Keto-PGFl Q均较前升高，ET，TXB：均较治疗前降低，差异具有 统计学意义(PO．05)。治疗后对照组N0比值较治疗组低，对照组 ET、TXB：较治疗组高，差异均有统计学意义(尸0．05)，两组 6-Keto—PGFl Q的差异无统计学意义(P0．05)。 (4)治疗组与对照组两组治疗前后的差值比较结果：NO、ET、 TXB2治疗组治疗前后的差值均较对照组大(Po．05)；6-Keto．PGFl Q治疗组与对照组的差值，差异无统计学意义(P0．05)。 结论：冠心病不同中医证型主要分布以气虚血瘀型、痰阻心脉型、 气滞血瘀型为主，以阳气虚衰型平均年龄最大；其中气滞血瘀型病变 平均支数最少、Gensini积分最低，阳气虚衰型病变平均支数最多、 Gensini积分最高。气滞血瘀型、气虚血瘀型，多见于单支病变；痰 阻心脉型、气阴两虚型，多见于双支病变；阳气虚衰型多见于多支病 变。所以冠脉病变、Gensini积分与冠心病中医证型有关联。气虚痰 瘀型冠心病患者治疗组和对照组相对于健康组而言，内皮功能均有损 害。经治疗后对照组、治疗组的NO、ET、TXB2、6-Keto．PGFl Q较 治疗前均有改变。治疗后治疗组NO，ET，TXB2疗效差值差异更大， 说明服用蛭龙活血通瘀胶囊的患者比单纯西医规范化治疗的疗效更 显著，内皮功能改善效果更好。 关键词：冠脉病变；冠心病；中医证型；内皮功能；Gensini积 分 万方数据 西南医科大学硕士学位论文The 西南医科大学硕士学位论文 The relationship between coronary lesions and TCM syndrome type and the effect of Zhilong Hongxue Tongyu capsule on vascular endothelial function in patients with Qi deficiency and phlegm blood stasis syndrome type of coronary heart disease(CHD) Abstract：0bjectiVe：(1)To investigate the relationship between TCM Syndromes of coronary heart disease(CHD)and coronary artery stenosis and Gensini SCOreS．(2)To observe the Zhilong Hongxue Tongyu capsule effecting on vascular endothelial function in patients with Qi deficiency and phlegm blood stasi s syndrome type of CHD． Methods：(1)Collected 37 1 Patients with CHD who were diagnosed by coronary arteriography(CAG)in Cardiac—Neurology department of The affiliated TCM hospital of XiNan medical university From May 20 1 3 to April 20 1 5．(2)Record the basic information and the remit of coronary angiography，type the TCM syndrome differentiation，calculate Gensini scores， fill in the case report form(ERr)，establish the detabases，etc．(3)The hospitalized patients from May 20 1 5 to September 20 1 5 who were diagnosed by CAG in our Department and belonged to Qi deficiency and phlegm blood stasis syndrome type were randomly divided into control group and treatment group，and selected healthy people