急性胰腺炎患者远期胰腺功能变化及生活质量评估-内科学(消化内科)专业论文.docxVIP

Abst Abstract IV IV ABSTRACT Background: Acute pancreatitis(AP) is an acute inflammatory disease of the pancreas that may also involve surrounding tissues or remote organs. It is well-known that AP is the common cause of diabetes mellitus (DM), which is classified as type-3C DM. The persistent impaired insulin secretion may contribute to type-3C DM. DM is a worldwide public health issues which threatens human health, the prevalence and the number of patients is increasing sharply, if DM is not promptly attended to，complications like ketoacidosis, lower extremities vascular lesions, diabetic retinopathy will happen as a result, thus making a research about the blood glucose metabolism and determining the optimal strategy for early management is utmost important. C-peptide is the secretory product of pancreaticβcell, which can be applied to distinguish the type of diabetes mellitus and know about the function of pancreatic βcell. Glycated serum protein can represent the average blood sugar in the past 1 or 2 weeks, and avoid the affect of blood-sugar level then. Pancreatic endocrine function and exocrine function connect with each other. Pancreatic exocrine dysfunction can not be ignored, and fecal elastase-1 is the the most common measurement. Whether the life quality of AP patients can be affected has aroused public’s attention.SF-36 short form is the most widely-used questionnaire which possesses high reliability and validity. After the release of revision of the Atlanta classification and definitions by international consensus, there is a lack of research about pancreas dysfunction and life quality in the long-term follow-up among MAP, MSAP and SAP in China. Objective: Make a research about pancreas function and life quality after AP. Methods: The 58 AP patients who discharged from the First Affiliated Hospital of Nanchang University during the year from 2005 to 2013 and paid visit at the gastroenterology outpatient clinic were enrolled. The mean time aft