玉屏风颗粒联合依巴斯汀治疗慢性荨麻疹疗效观察.docVIP

玉屏风颗粒联合依巴斯汀治疗慢性尊麻疹疗效观察 姚丽萍张剑叶田 (四川医科大学附属中医医院皮肤科646000) 【摘要】目的：探讨玉屏风颗粒联合依巴斯汀治疗慢性尊麻疹的临床疗效。 方法：选取126例慢性寻麻疹患者，随机分为观察组和对照组(各63例)，观察 组采用玉屏风颗粒联合依巴斯汀治疗，对照组口服依巴斯汀治疗，观察4周。观 察比较两组患者的临床治疗疗效和不良反应。结果：观察组有效率(96.83%)高 于对照组有效率(84.13%)高，两组比较差异有统计学意义；观察组未见明显不 良反应。结论：玉屏风颗粒联合依巴斯汀治疗慢性尊麻疹临床疗效确切，安全性 较高，值得临床推广使用。 【关键词】慢性寻麻疹；玉屏风颗粒；依巴斯汀；疗效观察 【中图分类号】R453 【文献标识码】A 【文章编号】2095-1752 (2015) 22-0239-02 Observation of clinical efficiency of jade screen particles combined with ebastine in treatment of chronic urticaria Yao Liping, Zhang Jian, Ye Tian, et al. Department of Dermatology, the Affiliated TCM Hospital of SiChuan Medical College, Luzhou, Sichuan Province, P. R. China 646000 【Abstract ] Objective To evaluate the efficacy of Jade screen particles plus ebastine for chronic urticaria. Methods A total of 126 patients with chronic urticaria were randomly assigned to receive either ebastine alone(control group)or ebastine plus jade screen particles (observation group), with 63 cases each. The clinical efficacy in the two groups was evaluated at 4 weeks of treatment and the patients were followed?up at 4 weeks of drug withdrawal. Results There were statistically sign讦icant differences between the observation group and the control group in the effective rate(96.83% vs. 84.13%), and no sign讦icant adverse drug reacti ons were no ted in the observati on group. Con clusi ons Jade scree n particles plus ebastine has remarkable clinical curative efficacy for chronic urticaria, which is worthy of clinical recommendation. 【Key words] Chronic urticaria; Jade screen particles; Ebastine; Clinical observati on 慢性寻麻疹是一种以红斑、风团为主要临床表现的慢性皮肤变态反应性疾病, 其病因及发病机制复杂。该病的治疗方法较多，但受多种因素影响，很难达到满 意疗效。本研究将2013年7月至2014年12月在本院接受诊治的126例慢性尊 麻疹患者分为观察组和对照组，其中观察组采用玉屏风颗粒联合依巴斯汀治疗， 而对照组仅给予依巴斯汀治疗，比较两组患者的临床疗效及不良反应，观察组取 得了较好的临床疗效，现将结果报道如下。 ?资料及方法 1.1资料来源 来源于我科2013年7月至2014年12月诊治的慢性尊麻疹患者126例，临 床上病因不明确，年龄16?60岁，性别不限。通过伦理委员会批准，经患者知 情同意，患者能够按要求完成治疗疗程、复诊、检查及随访。 1.2样本选择 入选标准：符合慢性尊麻疹诊断标准[1],病程ge;6周，临床表现主要为红 斑、风团，持续时间le;24小吋，伴有瘙痒。排除标准：（1）对玉屏风颗粒或 依巴斯汀过