CdSe量子点的制备及其被聚乳酸包被的研究.PDF

第 40 卷第 4 期 中南大学学报( 自然科学版) Vol.40 No.4 2009 年 8 月 Journal of Central South University (Science and Technology) Aug. 2009 CdSe 量子点的制备及其被聚乳酸包被的研究 谷 俐，李 菲，张 洋，谷丹青 (嘉兴学院 生物与化工学院，浙江 嘉兴，314001) 摘 要：以巯基乙酸为稳定剂，制备CdSe 量子点，并考察聚乳酸对量子点的包被。采用透射电镜对 CdSe 量子点 被聚乳酸包被前后的形貌进行观察，采用 X 射线粉末衍射、紫外可见吸收光谱、荧光光谱和荧光显微镜对产物进 行分析和表征。研究结果表明：CdSe 为闪锌矿型(立方形) 的球形纳米晶，量子点的平均尺寸为4 nm ，具有明显的 量子尺寸效应和较强的荧光强度；组装聚乳酸的量子点相对于纯的量子点尺寸明显增大(40 nm)，荧光强度有所增 强，且量子点被包裹在内核，具有明显的核壳结构。 关键词：量子点；聚乳酸；包被；荧光 中图分类号：TQ050.4+3 文献标识码：A 文章编号：1672−7207(2009)04−0904−05 Preparation of CdSe quantum dots and coating with polylactide GU Li, LI Fei, ZHANG Yang, GU Dan-qing (College of Biological and Chemical Engineering, Jiaxing University, Jiaxing 314001, China) Abstract: With thioglycollic acid as stablizing agent, cadmium selenide (CdSe) quantum dots were prepared, and the coating of CdSe with polylactide was studied. By means of X-ray diffractrometry, ultraviolet absorption spectroscopy, spectrofluorimetry, transmission electronic microscope and fluorescent microscope, CdSe was identified as cubical nanocrystal with an even size of 4 nm, and enjoys obvious quantum size effect and strong fluorescence. Compared with pure quantum dots, CdSe quantum dots coated with polylactide are characterized with large size, typical nuclear shell structure and stronger fluorescence. Key words: quantum dots; polylactide; coating; fluorescence 量子点(Quantum dots，QDs)具有优良的光谱特征 有利于增强荧光示踪剂与生物素的亲和力和特异性。 和光化学稳定性，荧光纳米材料作为荧光标记物，与 人们对量子点表面包裹壳聚糖衍生物、二氧化硅、磁 传统有机荧光染料相比，具有激发谱线范围宽、发射 流体等的研究取得了进展[10−13] 。聚乳酸以其良好的生 谱线窄、发光效率高、发光颜色可调，并且光稳定性