碳纳米管在生物传感器中的应用.pptVIP

Applications of carbon nanotubes in biosensors Outline Preface Functionalization of CNTs Novel applications Future outlook Preface The recognition or catalytic properties of the biomaterials Proteins/enzymes, antigens/antibodies, or DNA , et al. Special structural features and properties of CNTs CNT is a tubular form of carbon with diameter as small as 1 nm. Length: few nm to microns. Functionalization of CNTs Assemble with small molecules CNTs and polymer Mental nanoparticles and CNTs Fill CNTs with nanoparticles CNTs is insoluble in water, so functionalization of CNTs is necessary. Assemble CNTs with small molecules Assemble CNTs with small molecules and proteins Chitosan-grafted multi-walled carbon nanotubes Although acid treated CNTs are water-soluble, the carbonyl (C=O), carboxyl (–COOH), and/or hydroxyl (–OH) groups on their surfaces might lead to higher toxicity. Selective attachment of gold nanoparticles to nitrogen-doped carbon nanotubes Electrochemical biosensing platforms using platinum nanoparticles and carbon nanotubes Platinum nanoparticles with a diameter of 2-3 nm were prepared and used in combination with single-wall carbon nanotubes (SWCNTs) for fabricating electrochemical sensors with remarkably improved sensitivity toward hydrogen peroxide. Bioelectrochemically functional nanohybrids through co-assembling of proteins and surfactants onto carbon nanotubes: facilitated electron transfer of assembled proteins with enhanced faradic response Applications Biopolymer and Carbon Nanotubes Interface Prepared by Self-Assembly Microperoxidase-11 HRTEM images of Fc@SWNTs (A) and Fc@SWNTs gel Ferrocene Peapod Modified Electrodes Peptide nanotube-modified electrodes for enzyme-biosensor applications The conductive properties of CNT– mediate electron transfer reactions with electroactive species in solution F. Patolsky, Y. Weizmann, I. Willner, Angew. Chem. 2004, 116, 2165 ± 2169; Angew. Chem. Int. Ed. 200