内科学英文课件:Rheumatology 101.pptx

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Rheumatology 101;Contents;What is rheumatology;What is rheumatology;What are rheumatic diseases;Systemic lupus erythematosus;Rheumatoid arthritis;Ankylosing spondylitis;Scleroderma;Dermatomyositis;Gout;Diagnose a rheumatic disease;;Labs: Routines: CBC, Urine, ESR, CRP, Ig, Complement, etc Autoantibodies: ANA, ENA, aCL, LA, anti-dsDNA, ANCA, RF, anti-CCP, etc;ANAs(antinuclear antibodies) are autoantibodies that bind to contents of the cell nucleus. ENAs (Extractable nuclear antigens) are a group of autoantigens that were originally identified as antibody targets in people with autoimmune disorders. They are termed ENA because they can be extracted from the cell nucleus with saline. The ENAs consist of ribonucleoproteins and non-histone proteins, named by either the name of the donor who provided the prototype serum (Sm, Ro, La, Jo), or the name of the disease setting in which the antibodies were found (SS-A, SS-B, Scl-70).;Diagnose a rheumatic disease;Diagnose a rheumatic disease;Medication for rheumatic diseases;Biologics;Biologics;Target therapy ;Challenges and oppotunities;Thank You !

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