氟比洛芬酯防治丙泊酚注射痛临床探索.docxVIP

氟比洛芬酯防治丙泊酚注射痛临床 探索 【摘要】 目的 观察氟比洛芬酯防治丙 泊酚注射液注射痛的效果。方法 90例ASA I?n级采用丙泊酚注射液诱导全麻病人， 随机分成六组，各15例。A组静推氟比洛芬 酯5ml（含量50mg）, 60min后开始丙泊酚注 射液诱导麻醉；B组静推氟比洛芬酯5ml, 30min后开始丙泊酚注射液诱导麻醉； C组 静推氟比洛芬酯5ml, 10min后开始丙泊酚 注射液诱导麻醉；D组静推氟比洛芬酯5ml 后用压脉带扎于肘部60秒后开始静推丙泊 酚注射液麻醉诱导；E组静推氟比洛芬酯60s 后开始静推丙泊酚注射液麻醉诱导； F组静 推氟比洛芬酯5ml后即刻开始丙泊酚注射液 麻醉诱导。 结果 疼痛发生率及疼痛评分： A组、B组与C组比较差异有显着性，A组与 B组比较差异无显着性，E组、F组与D组比 较差异有显着性，E组或F组与A组或B组 比较差异无显着性，D组与A、B组比较差异 有显着性。 结论 氟比洛芬酯对预防丙泊酚 注射液注射痛有效，用药后即刻予丙泊酚注 射液时对注射痛预防效果最好。 【关键词】氟比洛芬酯丙泊酚注射痛 [Abstract 】Objective To observe the clinical effect of using flurbiprofen axetil injection in treating pain on propofol injection . Methods 90 cases of ASA卜 2 grade patients under propofol-induced anaesthesia were divided randomly into 6 groups with 15 patients in each group . In group A ,5 ml flurbiprofen axetil was intravenous injected 60 min before propofol-induced anaesthesia ; in group B, 5 ml flurbiprofen axetilwas intravenous injected 30 min before propofol-induced anaesthesia ;in group C, 5 ml flurbiprofen axetilwas intravenous injected 10 min before propofol-induced anaesthesia; in group D, 5 ml flurbiprofen axetilwas intravenous injected , then elbow was pressed with blood pressure cufffor 60 sec before propofol-induced anaesthesia; in group E , 5 ml flurbiprofen axetilwas intravenous injected 60 sec before propofol-induced anaesthesia;in group F, propofol-induced anaesthesia began right aftger 5 ml flurbiprofen axetilwas intravenous injected .The injecting speed remained constantly . Pain of injection was ranked according to Ambesh s pain score (none, mild, moderate, and severe). Results In pain s incidence rate and ranking : there was significant difference between group A and group C , group B and group C , there was no significant difference between group A and group B, there was significant difference between group E and group D , group F and group D , there was no significant difference between group E and F compared with group A and group B, compared with group A and group B ,the