(工具篇)S4E26环状RNA常用数据库介绍总结.docxVIP

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(工具篇)S4E26环状RNA常用数据库介绍总结.docx

工具篇) S4E26 环状 RNA 常用数据库介绍总结 circBase 网址: /Thousands of circular RNAs (circRNAs) have recently been shown to be expressed in eukaryotic cells [Salzman et al. 2012, Jeck et al. 2013, Memczak et al. 2013, Salzman et al. 2013]. Here you can explore public circRNA datasets and download the custom python scripts needed to discover circRNAs in your own (ribominus) RNA-seq data. 数据库功能: Sequence-based searchSearch the database by identifier, gene description, genomic position, or their lists.Retrieve dataset slices by defining a set of conditions (table browser).Export tables in a variety of formats.Export FASTA files containing genomic sequence. 比如我们想查询 FoxO3 相关的环状 RNA ,可以直接在搜索框输入 FoxO3 , 结果如下: 可以看到人的两条和小鼠中的三条 circRNA ,并可进一步点 开查看。 CircNet : a database of circular RNAs derived from transcriptome sequencing data 网址: .tw/ 基于转录组测序的数据 建立的数据库,收录以下信息 novel circRNAs,integrated miRNA-target networks,expression profiles of circRNA isoforms,genomic annotations of circRNA isoforms (e.g. 282 948 exon positions), andsequences of circRNA isoforms. 比如我们想 查询 FoxO3 相关的环状 RNA ,可以直接在搜索框输入 FoxO3 ,结果如下: 如图所示,不仅显示了FoxO3 如图所示,不仅显示了 FoxO3 相关的环状 RNA circ-FOXO3.1 ,还显示了 microRNA ,右侧上面显示 circ-FOXO3.1 在染色体上的位置, 右侧下面可以根据位置对 circ-FOXO3.1 进行查询显示,右侧上面点击 Expression 表 达显示在不同组织中的表达水平: deepbase :a platform for annotating and discovering small and long ncRNAs (microRNAs, siRNAs, piRNAs...) from next generation sequencing data. 网址: / 这个数据库的的功能: deepView Genome Browser: visualization mapmicroRNAs and other ncRNAs expression patternpredicted RNA clusterspredicted microRNAspredicted snoRNAsbrowse microRNAs and ncRNA-associated small RNAsnasView Browser: comparisons of multiple libraries for ncRNAsbrowse promoter-associated and exon-associated small RNAsbrowse repeat-associated small RNAslibView Browser: comparisons of multiple librariescommon search or Search homologous reads 包括的信息比较全, 功能强大, 除了 circRNA 外, lncRNA 等信息也有,既可以浏览,也可 以搜索。如果要搜索 circRNA ,可以直接打开网 址:htt p: ///dee pBase/browse_circRN A.php?SClade=mammalS

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