药妆行业“十二五”规划调研与发展。。.pptxVIP

交通大学医学院附属仁济医院消化科上海市消化疾病研究所;Diarrhea;Pathophysiological mechanisms;Pathophysiological mechanisms;secretory diarrhoea;Cholera: the simplified version;Verner-Morrison syndrome (VIP associated);carcinoid syndrome;gastrinoma ;gastrinoma;Pathophysiological mechanisms Osmotic diarrhea It caused by accumulation of the followings in the gut lumen ;osmotic diarrhoea;;Calculation of osmotic gap; Pathophysiological mechanisms Decreased intestinal surface area and/or intestinal absorption E: surgical removal; malabsorption syndrome; ; Pathophysiological mechanisms Rapid transit of intestinal contents (shortened transit time) ;Etiology;Etiology;Acute Diarrhea Food poisoning bacterial, plants, chemical poison(arsenic,...) Systematic diseases (influenza, sepsis, measle, etc) Miscellanous Allergic diseases Allergic purpura, enteropathy.. endocronic diseases (ZES, etc.) Drugs: laxatives, 5-Fu, etc.;food poisoning;chinese restaurant syndrome;Etiology;Chronic Diarrhea;Endoscopic image: infectious colitis in 7-year-old girl;lower small bowel disease;upper small bowel disease;large intestine causes;gastric causes;pancreatic causes;endocrine related;functional causes irritable bowel syndrome;classification of diarrhoeal disease by time-course; Symptoms Acute diarrhea duration less than 2 weeks ;onset: Abrupt frequent, small fecal discharge Cramping abdominal pain, tenesmuse stool: increased Routin Ex severe cases: dehydration, electrolyte disturbances, metabolic acidosis, collapse hypovolumia, tetany.;Symptoms;Chronic diarrhea Symptoms Onset: gradual/insidious Diarrhea of variable severity Diarrhea alternate with constipation Colicky abdominal pain, distention ;intestinal causes;intestinal causes;stool watery, bloody, steatorrhea contains: inflammatory cells/mucus/pus/indigested food severe/long-standing cases: weight loss, malnutrition, edema, multy vits deficiency, malabsorption, wasting, edema, bone pain;Accompanied Symptoms;Diagnostic P