局部晚期非小细胞肺癌行三维适形放疗加NP方案同期化疗.doc

局部晚期非小细胞肺癌行三维适形放疗加NP方案同期化疗.doc

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局部晚期非小细胞肺癌行三维适形放疗加NP方案同期化疗 目录 TOC \o "1-9" \h \z \u 目录 1 正文 1 文1:局部晚期非小细胞肺癌行三维适形放疗加NP方案同期化疗 1 1 资料与方法 3 2 结 果 5 3 讨 论 5 文2:鸦胆子油乳注射液配合NP方案化疗治疗非小细胞肺癌 7 1 资料与方法 8 2 结 果 9 3 讨 论 10 参考文摘引言: 12 原创性声明(模板) 13 文章致谢(模板) 14 正文 局部晚期非小细胞肺癌行三维适形放疗加NP方案同期化疗 文1:局部晚期非小细胞肺癌行三维适形放疗加NP方案同期化疗 A looking-forward study with three-dimeional conformal radiotherapy plus NP scheme [Abstract] Objective: To evaluate the results and complicatio of 3D conformal radiotherapy combined with the chemotherapy for local advanced none small cell lung cancer (NCSLC). Method: Twelve patients in the study group were received induction chemotherapy 2 cycles navelbine ( 25 mg/m2 d1、d5 ) and cisplatin ( 80 mg/m2 d1 or 25 mg/m2 d1-3 ) followed by conventional radiotherapy (2 Gy/f, 5 f/w, totally 40 Gy), then by three-dimeional conformal radiotherapy boosted to TD 30 to 34 Gy in conventional fractionation completed in 3 to weeks. Patients were received chemotherapy navelbine (25 mg/m2 d1、d8 ) and cisplatin (25 mg/m2 d1、d8 ) for every 28 days in radiotherapy interval (Saturday or Sunday). Fourteen patients in control group were received induction chemotherapy and conventional radiotherapy which were the same as in study group, then followed by conventional radiotherapy with shrinkage fields covering the primary tumor and metastatic lymph node region had boost to 26~30 Gy in to 3 weeks. The patients hadn't received any chemotherapy while radiotherapy , but two to four coues sequential chemotherapy of NP scheme were performed after radiotherapy which were the same doses and medication as induction chemotherapy. Results: The 1-year survival in study group were 92% and 2-year were 61% and 57% and 14% respectively in control group respectively (log-rank analysis P<). All patients had tolerated the toxic and side effects and completed treatment plan in two groups. Conclusio: 3D-CRT plus NP scheme synchronization chemotherapy for NCSCLC has improved the local control rate and impr

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