乳腺癌骨转移的诊治课件.pptVIP

乳腺癌骨转移和骨相关疾病的诊断和治疗 Diagnosis and treatment of bone metastasis of breast cancer ppt 课件 1 乳腺癌骨转移和骨相关疾病的诊断和治疗 Diagnosis and treatment of bone metastasis of breast cancer ppt 课件 1 流行病学 Epidemiology ? 骨转移的比例仅次于肺、肝脏的转移 ? The ratio of bone metastasis is secondary to lung and liver ? 通常为 多发 ，单发转移者仅占 10% ? Usually for multiple bone metastasis,only 10% for single ? 80% 为 中轴骨 ，如脊柱和骨盆 ? 80% for axial skeleton , such as the spine and pelvis ppt 课件 2 目 录 Catalogue 一． 乳腺癌骨转移概述 1. Overview 二 . 乳腺癌骨转移诊断方法 2. Diagnostic method 三 . 乳腺癌骨转移临床表现 3. Clinical manifestation 四 . 乳腺癌骨转移治疗 4. Treatment ppt 课件 3 概 述 Overview ? 骨转移是乳腺癌 最常见 的 远处转移 部位 ? Bone metastasis is the most common distant metastases in breast cancer patients ? 晚期乳腺癌骨转移发生率为 65% ～ 75% ? The incidence of bone metastasis in terminal breast cancer is 65% ～ 75% ? 骨痛、骨相关事件〔 SREs 〕及生活质量降低是乳腺癌骨转 移的常见并发症 ? Bone pain, bone related events (SREs) and reduced quality of life are common complications of bone metastasis of breast cancer 参考文献 references ? 1.Coleman RE. Cancer Treat Rev. 2001 Jun;27(3):165-76. 2.John R. Johnson, Grant Williams,et al. J Clin Oncol 21:1404-1411. 3.Kinnane N. Eur J Oncol Nurs. 2007;11 Suppl 2:S28-31. Epub 2007 Sep 4. ppt 课件 4 诊断方法 Diagnosis ? 骨转移 初筛 诊断方法：骨放射性核素扫描〔 ECT 〕 ? The preliminary screening method of bone metastasis ： ECT ? 推荐用于出现骨疼痛、骨折、 AKP 升高、或高钙血症等可疑骨转移的常规初筛诊断检查 ? It is recommended to be used for patients of bone pain, fracture, AKP elevation, or hypercalcemia ? 乳腺癌分期＞ T3N1M0 患者常规检查 ? Routine examination of patients with breast cancer stage T3N1M0 ? 复发转移乳腺癌 患者的常规检查 ? Routine examination of patients with recurrent metastasis ppt 课件 5 ? 骨转移的影像学 确诊 检查方法：骨 X 线 / CT /MRI ? Confirmed Radiographic diagnosis of bone metastasis:X- ray/CT/MRI ? 60%-78% 溶骨性 破坏、 10%-20% 成骨性、 12%-20% 混合性 ? Osteolysis 60%-78%, ossify 10%-20%, mixed 12%-20% ? 骨活检：诊断乳腺癌骨转移的 金标准 ? Biopsy: D