孕妇外周血中胎儿DNA及瘦素含量与子痫前期发病的关系医学（医学资料）.docVIP

孕妇外周血中胎儿DNA及瘦素含量与子痫前期发病的关系医学（医学资料） 文档信息 主题： 关于“医学心理学”中“妇产科学”的参考范文。 属性： F-01L7EB，doc格式，正文24306字。质优实惠，欢迎下载！ 适用： 作为医学资料、医学资料写作的参考文献，解决如何写好实用应用文、正确编写文案格式、内容摘取等相关工作。 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：孕妇外周血中胎儿DNA及瘦素含量与子痫前期发病的关系医学 2 1 对象与方法 3 2 结 果 5 3 讨 论 5 文2：孕妇血浆中胎儿游离DNA及抗DNA抗体与子痫前期的相关性研究 7 1 临床资料 8 2 结果 10 3 讨论 11 参考文摘引言： 13 原创性声明（模板） 15 文章致谢（模板） 15 正文 孕妇外周血中胎儿DNA及瘦素含量与子痫前期发病的关系医学（医学资料） 文1：孕妇外周血中胎儿DNA及瘦素含量与子痫前期发病的关系医学 ［ABSTRACT］ObjectiveTo study the concentration of fetal DNA and leptin in maternal blood and their relatiohip with preeclampsia. MethodsThirty gravida with preeclampsia, mild 18 and severe 12, were enrolled in this study. The blood was taken at around 20 weeks of gestation, at the oet, and six hou after parturition. And 30 normal gravida served as controls, their blood was taken accordingly. All of this two groups were confirmed ultrasonographically to have a male fetus. Fetal DNA and leptin in all the pregnant women plasma were measured by fluorescent quantitative polymerase chain reaction (FQPCR) and radioimmunoassay (RIA). ResultsThe fetal DNA level of the mild patients at about 20week gestation and at oet was remarkably higher than that the normal control, and that of the severe ones was higher than that of the mild ones （F=，;q=;P). At six hou after dilivery, the fetal DNA level of the patients was significantly higher than that of the control group （t′=，P）. During the attack of preeclampsia, the leptin concentration was significantly higher than that of the normal control, and that of the severe cases was higher than that of the mild ones （F=’q=，;P). A positive correlativity was observed between the fetal DNA and leptin concentration in the patients （r=， P ）.ConclusionThe concentration of fetal DNA and leptin in maternal blood closely correlates with preeclampsia. ［KEY WORDS］eclampsia; DNA; leptin 妊娠高血压综合症是妊娠期特有疾病，但其病因至今尚未明确，而且对它的预测没有明确的指标。子痫前期的主要病理学因素可能是由于滋养层不能有效地侵入蜕膜和动脉管壁，导致胎盘缺陷，着床较浅，致滋养细胞缺血低氧［1］。而有研究证明胎盘低氧是