不同剂量聚乙二醇电解质溶液在结直肠癌术后患者肠道准备中的效果研究.docxVIP

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不同剂量聚乙二醇电解质溶液在结直肠癌术后患者肠道准备中的效果研究.docx

不同剂量聚乙二醇电解质溶液在结直肠癌术后患者肠道准备中的效果研究   [摘要]目的研究不同劑量聚乙二醇(polyethyleneglycol,peg)电解质溶液在结直肠癌(colorectalcarcinoma,crc)术后患者肠道准备中的效果及不良反应情况。方法选取2017年1月~2019年1月在南京医科大学第二附属医院消化内科收治的行结肠镜检查的crc术后患者共320例,依据peg溶液剂量分为2l-peg组和4l-peg组,每组160例。比较两组患者不良反应情况,以及分别在保留右半结肠crc术后患者、右半结肠切除crc术后患者中peg剂量对患者肠道清洁度的影响。结果2l-peg组与4l-peg组在肠道准备导致crc术后患者出现恶心、呕吐、腹痛、腹胀等不良反应无明显差异(p0.05),但2l-peg组睡眠质量较好,差异有统计学意义(p0.05)。对于保留右半结肠crc术后患者,4l-peg组肠道清洁效果优于2l-peg组,差异有统计学意义(p0.05);对于右半结肠切除crc术后患者,2l-peg组与4l-peg组肠道清洁效果无明显统计学差异(p0.05)。结论依据crc术后患者是否保留右半结肠,选择不同剂量的peg溶液有利于提高crc术后患者肠道准备质量及睡眠质量。   [关键词]结直肠癌术后;肠道准备;聚乙二醇;结肠镜   [中图分类号]r473[文献标识码]b[文章编号]1673-9701(2019)36-0155-04   effectsofdifferentdosesofpolyethyleneglycolelectrolytesolutioninintestinalpreparationofpatientsaftercolorectalcarcinomasurgery   xuyi1,2,3duanpeibei1,2   1.schoolofnursing,nanjinguniversityoftraditionalchinesemedicine,nanjing210023,china;2.departmentofnursing,affiliatedhospitalofnanjinguniversityoftraditionalchinesemedicine(jiangsuhospitaloftraditionalchinesemedicine),nanjing210029,china;3.departmentofnursing,thesecondaffiliatedhospitalofnanjingmedicaluniversity,nanjing210011,china   [abstract]objectivetostudytheeffectsandadversereactionsofdifferentdosesofpolyethyleneglycolelectrolyte(peg)solutionintheintestinalpreparationofpatientsaftercolorectalcarcinoma(crc)surgery.methodsatotalof320patientswhounderwentcolonoscopyaftercrcsurgeryinthedepartmentofgastroenterology,thesecondaffiliatedhospitalofnanjingmedicaluniversityfromjanuary2017tojanuary2019wereenrolledanddividedintothe2l-peggroupandthe4l-peggroupaccordingtothedoseofpegsolution,with160patientsineachgroup.theadversereactionsofthetwogroupswerecomparedandtheeffectsofdifferentpegdosesontheintestinalcleanlinessofthepatientskeepingtherightcolonandthepatientshavingtherightcolonremovedaftercrcsurgerywerecompared.resultstherewasnosignificantdifferencesintheintestinalpreparationinducedadversereactionssuchasnausea,vomiting,abdominalpainandabdominaldistensionaftercrcsurgerybetweenth

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