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Key words;Case Introduction ;Risk of Prosthetic Valve Thrombosis;Factors increasing the risk of PVT;Considerations during Anticoagulation;Warfarin;Heparin;Anticoagulation Management;Thrombosis Rate; As soon as her pregnancy is confirmed:
LMWH(tinzaparin): 7500 units Bid., and stopping warfarin.
Warfarin: recommenced at 16 wks and stopped at 36 wks.
LMWH (enoxaparin): 90mg Bid.
Aspirin: 150mg, Qd, together with LMWH.
;Monitoring LMWH Therapy;At 38 weeks: a planned induction of labor.
Heamatology Department: joined for assistance.
Full blood count and anti-Ⅹa level 1.2 IU/ml
Analgesia in labor: opioids, N2O+O2(Entonox).
Epidural analgesia≧24hrs after last LMWH
Recommence LMWH ≧2hrs after Epi. Catheter removal
Epidural heamotoma: risk reduced but still in existence
Uneventful labor(SVD), healthy boy, discharged home later.
Anticoagulation therapy
Warfarin: restarted following delivery, INR2.0~3.0.
Enoxaparin: used in pregnacy.
;10 days later: vaginal bleeding, light headed.
Vital signs and blood tests: within normal limits.
HR: 64bpm, BP:110/72mmHg, RR:14/min.
Hb:112g/L, WBC:5.8E9/L, Plt:195E9/L
APTT ratio:1.2, Fibinogen:2.8g/dl, anti-Ⅹa level:1.32 IU/ml
;Causes of PPH;Cause and Management;One surgical option available --placement of an intrauterine balloon;Case Introduction;Uterine Artery Embolisation;Complications of UAE;Outcome of the Patient;Summary;感谢您的观看!
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