MTPG-DataSheet-生命科学试剂-MedChemExpress.pdf

Hotline: 400-820-3792 Inhibitors • Screening Libraries • Proteins www.MedChemE MTPG Cat. No.: HY-101247 CAS No.: 169209-66-9 分⼦式: C₁₀H₁₁N₅O₂ 分⼦量: 233.23 作⽤靶点: mGluR 作⽤通路: GPCR/G Protein; Neuronal Signaling 储存⽅式: Please store the product under the recommended conditions in the Certificate of Analysis. BIOLOGICAL ACTIVITY ⽣物活性 MTPG 是⼀种有效的 mGluR2 与 mGluR3 拮抗剂。MTPG 可阻断脑缺⾎预处理诱导的脑缺⾎耐受。MTPG 也能 显著减弱 L-CCG-1 对 KCl 诱发的多巴胺释放的抑制作⽤ [1]。 IC50 & Target mGluR2, mGluR 3 [1] REFERENCES [1]. Chaki S, et al. Group II metabotropic glutamate receptor-mediated regulation of dopamine release from slices of rat nucleus accumbens. Neurosci Lett. 2006;404(1-2):182-186. [2]. Feng RF, Li WB, Liu HQ, et al. Sheng Li Xue Bao. 2003;55(3):303-310. McePdfHeight Caution: Product has not been fully validated for medical applications. For research use only. Tel: 400-820-3792; 021 Fax: 021 E-mail: tech@MedChemE 1/1 Master of Bioactive Molecules — 您⾝边的抑制剂⼤师