CBCT图像引导下胸部肿瘤放射治疗摆位误差分析及其对剂量分布的影响的中期报告.docxVIP

CBCT图像引导下胸部肿瘤放射治疗摆位误差分析及其对剂量分布的影响的中期报告 摘要：本研究旨在评估采用锥束CT (CBCT) 摆位图像引导下胸部肿瘤放射治疗的摆位误差情况以及其对剂量分布的影响。研究共纳入12例患者，治疗过程中通过CBCT图像引导进行摆位校正，并采用强度调制放疗技术 (IMRT) 进行放疗计划设计。摆位误差数据通过CBCT图像再注册后进行分析。结果显示，在摆位校正之前主要误差来源于患者呼吸运动导致的姿态变化，而在摆位校正后误差显著降低。尽管局部剂量分布呈现出一定程度的改变，但整体剂量分布与计划剂量分布基本一致。因此，CBCT图像引导下胸部肿瘤放射治疗可以有效地降低摆位误差并保证放疗计划的实施精度。 关键词：锥束CT；胸部肿瘤；放射治疗；摆位误差；剂量分布 Abstract: The aim of this study was to evaluate the positioning errors and their effects on the dose distribution for thoracic tumor radiotherapy using cone-beam computed tomography (CBCT) guidance. Twelve patients were included in the study, and the treatment process involved positional correction guided by CBCT and intensity-modulated radiation therapy (IMRT) planning. The positioning errors were analyzed after CBCT registration. The results showed that the main source of error before positional correction was caused by the patients breathing motion, and the errors were significantly reduced after positional correction. Although the local dose distribution showed some changes, the overall dose distribution was in close agreement with the planned dose distribution. Therefore, thoracic tumor radiotherapy using CBCT guidance can effectively reduce the positioning errors and ensure the implementation accuracy of the treatment plan. Keywords: Cone-beam computed tomography; Thoracic tumor; Radiotherapy; Positioning error; Dose distribution.