气相色谱-质谱法同时测定护手霜中的4种丁二醇.docxVIP

气相色谱-质谱法同时测定护手霜中的4种丁二醇 孙银;黄国平 【摘要】采用超声萃取-气相色谱-质谱法同时测定护手霜中的4种丁二醇.1.000 0 g样品用10 mL甲醇在70OC超声萃取30 min,萃取液过0.45口 m有机滤膜后，在 DB-23毛细管色谱柱上分离，质谱分析中采用电子轰击离子源和全扫描模式.4种丁 二醇的线性范围均为0.50~100.0mg.L-1,检出限(3S/N)均为0.10 mg-L-1.加标回 收率为85.7%~ 102%,测定值的相对标准偏差(n=6)小于9.0%.%GC-MS combined with ultrasonic extraction was applied to the simultaneous determination of 4 butanediols in hand-cream.The sample (1.000 0 g) was ultrasonically extracted with 10 mL of methanol at 70 Cfor 30 min.After being filtrated with 0.45 pm organic filter,the extrate was seperated on a DB-23 capillary chromatographic colurnr.Electron impact io