颈动脉夹层抗凝vs抗血小板.ppt

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感谢大家观看第31页,共31页,星期六,2024年,5月***47岁男性患者,钓鱼过程中突发眩晕,立即送医院,当时查体仅仅存在眼球震颤立即CT无异常发病后24小时突然头痛恶心呕吐复查CT提示双侧小脑半球梗死18小时后突发意识丧失,复查CT提示SAHDSA过程中死亡**TranscranialDopplerintheEvaluationofInternalCarotidArteryDissectionJayashreeSrinivasan,MD;DavidW.Newell,MD;MatthiasSturzenegger,MD;MarcR.Mayberg,MD;H.R.Winn,MD

theDepartmentofNeurologicalSurgery,UniversityofWashingtonSchoolofMedicine,Seattle;andtheDepartmentofNeurology,UniversityofBern(Switzerland)(M.S.).CorrespondencetoDavidW.Newell,MD,DepartmentofNeurologicalSurgery,UniversityofWashingtonSchoolofMedicine,Box359766,Seattle,WA98104.

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BackgroundandPurposeAsubjectwithdissectionoftheinternalcarotidartery(ICA)maypresentwithavarietyofsymptoms,fromheadachetostroke.Thusfar,ithasnotbeenpossibletoidentifythesubsetofpatientsatriskforcerebralischemia.Becausethemajorityoftheseischemiceventsaresecondarytoembolicphenomena,weusedtranscranialDoppler(TCD)evaluationwithembolimonitoringtostudy17consecutivepatientswithICAdissectiontreatedatHarborviewMedicalCenter,Seattle,Wash,duringa2-yearperiodfrom1992until1994.MethodsTenpatientswithICAdissectionsecondarytotraumaandsevenwithspontaneousICAdissectionwerediagnosedbycarotidangiographyandstudiedbyTCDfromthetimeofdiagnosisthroughinitiationoftherapy.Embolimonitoringwasperformedinthemiddlecerebralartery(MCA)ipsilateraltothedissectionattheinitialevaluationandintermittentlythereaftertoensurethattheembolistoppedwithtreatment.ResultsEmboliweredetectedintheMCAdistaltothedissectionin10of17patients(59%).PatientswithmicroembolidetectedbyTCDpresentedwithastroke(70%)muchmorefrequentlythanthosewithoutemboli(14%)(P=.0498).Thepresenceofapseudoa

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