S49076-hydrochloride-生命科学试剂-MCE.pdf

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S49076hydrochloride

Cat.No.:HY-12965A

CASNo.:1265966-31-1

分⼦式:C₂₂H₂₃ClN₄O₄S

分⼦量:474.96

作⽤靶点:FGFR;c-Met/HGFR

作⽤通路:ProteinTyrosineKinase/RTK

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

溶解性数据

体外实验DMSO:≥31mg/mL(65.27mM)

*≥meanssoluble,butsaturationunknown.

Mass

Solvent

1mg5mg10mg

Concentration

制备储备液1mM2.1054mL10.5272mL21.0544mL

5mM0.4211mL2.1054mL4.2109mL

10mM0.2105mL1.0527mL2.1054mL

BIOLOGICALACTIVITY

⽣物活性S49076hydrochloride是新颖⾼效的MET,AXL/MER和FGFR1/2/3抑制剂，IC50值⼩于20nM。

客户使⽤本产品发表的科研⽂献

•NatCommun.2019Apr18;10(1):1812

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REFERENCES

1/2MasterofBioactiveMolecules—您⾝边的抑制