《病理学》7 Diseases of the Digestive System-英文教学课件(非AI生成).pptx

《病理学》7 Diseases of the Digestive System-英文教学课件(非AI生成).pptx

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DiseasesoftheDigestiveSystem

;Gastritis

Pepticulcers

Carcinomasofthealimentarytract

Viralhepatitis

Livercirrhosis

Commonnon-viralliverdiseases

Primarycarcinomasoftheliver;

DigestiveSystem;mouth;DigestiveGlands;Relationwithdiseasesofothersystems

Cirrhosis→hepaticencephalopathy

Hepaticdiseases→renaldisease

(hepatorenalsyndrome)

Acutegastrointestinalinflammation

→disturbancesofwaterand

electrolytes

SLE→Chronichepatitis

Heartfailure→hepaticcongestion;Gastritis;Anacutemucosalinflammatoryprocess,usuallyofatransientnature

(病因复杂多样,发病机制尚不完全明确)

EtiologyandPathogenesis

1.Heavyusedrugse.g.aspirin

2.Excessivealcoholconsumption,

Heavysmoking

3.Systemicinflammation(Salmonllosis沙门菌)

4.Shockandseverestress(trauma,burns)

5.Physicaland?mechanicalinjury

6.Chemicalfactor

Suicideattempts:acidsandalkalietc.;MorphologicandClinicalfeatures;2.Chronicgastritis(慢性胃炎);CGclassifiedinto3forms

(BasesonEtiologyandPathogenesis)

themostcommonform-CGassociatedwithHelicobacterpylori(HP)

Thisforminflammationusuallyfocusestogastricantrumandpylorus.SoantralCGisthemostcommon.

HPassociatecloselywithCG

①HPinfectionispresentinabout90%ofCGpatients

②antibiotictreatment-promoteshealingofCG

;OthertwoformsofCG--muchlesscommon

①AutoimmuneCG(10%):

auto-antibodiesagainstparietalcells(壁细胞)andintrinsicfactor(内因子)

autoimmuneinjury

①glanddestructionandmucosalatrophy

②lossofintrinsicfactorproduction

(VitaminB12perniciousanemia)

Histologicdistribution:

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