Ebopiprant-hydrochloride-OBE022-hydrochloride-生命科学试剂-MCE.pdf

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Ebopipranthydrochloride

Cat.No.:HY-112284A

CASNo.:2005486-32-6

Synonyms:OBE022hydrochloride

分⼦式:C₃₀H₃₅ClFN₃O₅S₂

分⼦量:636.2

作⽤靶点:ProstaglandinReceptor

作⽤通路:GPCR/GProtein

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Ebopiprant(OBE022)hydrochloride是⼀个⼝服的、前列腺素F2α(PGF2α)受体的选择性拮抗剂，其对⼈和

⼤⿏FP受体的Ki值分别为1nM和26nM。

客户使⽤本产品发表的科研⽂献

•EMBOMolMed.2022Dec13;e16373.

•IntJMolSci.2023Apr10,24(8),7012.

Seemorecustomervalidationsonwww.MedChemE

REFERENCES

[1].OliverPohl,etal.OBE022,anoralandselectiveprostaglandinF2αreceptorantagonistasaneffectiveandsafemodalityforthe

treatmentofpretermlabor.JPharmacolExpTher.2018Aug;366(2):349-364.

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