组蛋白赖氨酸甲基化途径及其甲基转移酶与去甲基化酶概览.pdfVIP

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HistoneLysineMethylationPathway

MethylationDegree:+Mono†Di‡Tri

H4K20me

Methylases:

SET8/KMT5A(+)

NSD1/KMT3B(+,†)

ASH1L/KMT2H(+,†,

SUV420H1/KMT5B(†,‡)

SUV420H2/KMT5C(†,‡)

NSD2/KMT3G(+,†)

Demethylases:

JHDM1D/KDM7A(+,†)

PHF8/KDM7B(+，†)

H3K9me

甲基转移酶：

PRDM3/KMT8E(+)

PPRDM16/KMT8F(

G9a/EHMT2/KMT1