乳腺癌与甲状腺疾病相关性的临床研究.pdfVIP

Researchand 肿瘤研塞与j魅2013字3月第25卷第3期CancerClinic，March2013，Vnl．25，No．3 ·论著· 乳腺癌与甲状腺疾病相关性的临床研究 赵艳杰王睿斌宋雨光任军 【摘要】 目的探讨乳腺癌患者自身免疫与非自身免疫甲状腺疾病的发病情况。方法选择100例 乳腺癌手术患者，以同期相对应年龄无乳腺疾病及甲状腺疾病病史女性100名为对照组，通过临床检查、 B型超声、甲状腺素及抗体水平检查、细针穿刺活组织检查等对比甲状腺疾病的发病情况。结果乳腺 癌患者抗甲状腺过氧化物酶抗体明显高于对照组f(104．56±21，54)U／ml比(22．16±4．65)U／ml， P=0．030]。乳腺癌组自身免疫与非自身免疫甲状腺疾病的发病率高于对照组『38％(38／100)比17％ 非自身免疫甲状腺疾病的发病率高于非乳腺癌者。 【关键词】乳腺肿瘤； 甲状腺疾病 Cljllicalresearchonthe betweenbreastcancerand disorderZHA0 relationship thyroid Yanziie$。 WANG Medical Rui—bin，SONG of Shijitan Yu—guang,RENJun．4DepartmentOncology，BeringHospital， Medical 100038，China Capital University，Bering author：REN CorrespondingJun，Email：renjun9688@yahoo．con To theincidenceofautoimmuneandnonautoimmune 【Abstract】0bjectiveinvestigate thyroid diseasesin withbreastcancer．MethodsClinicalandultrasoundevaluationof patients thyroidgland． detectionofserum hormoneandrelated fine—needle of were thyroid antibodies，andaspirationthyroidgland in100breastcancer and100controIindividualsthe from2004to2008． performed patients duringperiod ResultsThemeanvaluesof antibodieswere inbreastcancer anti．thyroidperoxidase significantlyhigher in thanthatcontrol patients individuals【(104．56±21．54)U／mlVS(22．16“．65)Ulmt，(P=0，030)]．The incidenceratesofautoimmuneandnonautoimmunediseaseswere inbreastcancer thyroid higher patients thanthatincontrol 17％(17／100)，P=0．0009，26％(26／100)VS