新的芳杂环酰腙分子钳的微波无溶剂快速有效合成47927.pdfVIP

2010 年第30 卷 有 机 化 学 Vol. 30, 2010 第6 期, 871～876 Chinese Journal of Organic Chemistry No. 6, 871～876 ·研究论文· 新的芳杂环酰腙分子钳的微波无溶剂快速有效合成 石培育 刘玲玲 李晓蕊 赵志刚* 刘兴利 (西南民族大学化学与环境保护学院 成都 610041) 摘要 在微波辐射无溶剂条件下, 以间苯二酚为起始原料, 固体Al2O3 为载体, 设计并高产率地合成了 12 个新的芳杂 环酰腙分子钳人工受体. 其结构均经1H NMR, IR, MS 及元素分析确证. 同传统的方法相比, 该法具有简单、快速、高 效和对环境友好等优点. 利用紫外滴定光谱初步考察了这类分子钳对芳胺的识别性能. 关键词 酰腙; 分子钳; 微波辐射; 合成 Rapid and Efficient Synthesis of Novel Aryloxyacetyl Hydrazone Molecular Tweezers in Solvent-Free Conditions under Microwave Irradiation Shi, Peiyu Liu, Lingling Li, Xiaorui Zhao, Zhigang* Liu, Xingli (College of Chemistry and Environmental Protection Engineering, Southwest University for Nationalities, Chengdu 610041) Abstract Twelve new aryloxyacetyl hydrazone molecular tweezers have been designed and synthesized with high yields using solid Al O as supporter and resorcinol as the starting material in solvent-free condi- 2 3 1 tions under microwave irradiation. The structures of all molecular tweezers were characterized by H NMR, IR, mass spectra and elemental analysis. Compared with the conventional heating method, this method is simple, fast, efficient and eco-friendly. The recognition properties of these molecular tweezers for aromatic amines were investigated by UV-Vis spectral titration. Keywords aryloxyacetyl hydrazone; molecular tweezer; microwave irradiation; synthesis 分子钳是近年来开拓的一种新型人工受体模型, 在 骨架, 由间苯二氧乙酸