我院2007-2009年口服降糖药应用分析.pdfVIP

中国药物应用与监测2010年10月第7卷第5期 Chinese Journal of Drug Application and Monitoring, Vol.7, No.5, October 2010 我院2007 -2009年口服降糖药应用分析 魏钰茜，林 辉（解放军总医院药品保障中心，北京 100853 ） [摘要] 目的：了解我院口服降糖药使用现状及发展趋势，促进临床合理用药。方法：对我院2007 – 2009 年口服降糖药的销 售金额、用药频度（DDDs ）、日均费用（DDC ）等进行回顾性分析。结果：我院2007 – 2009 年口服降糖药销售金额呈上升趋 势，销售金额排在前三位的是阿卡波糖、盐酸二甲双胍片、格列美脲；DDDs 排序前三位的是阿卡波糖、盐酸二甲双胍片、格 列喹酮。结论：我院口服降糖药应用基本合理，新药用量呈上升趋势，高效、安全、依从性好的药物临床应用广泛。 [关键词] 降糖药；用药频度；日均费用；用药分析 [ 中图分类号] R969.3 [文献标识码] A [文章编号] 1672 – 8157(2010)05 – 0295 – 02 Utilization of oral hypoglycemic drugs in our hospital in 2007 -2009 WEI Yu-xi, LIN Hui(Pharmaceutical Care, PLA General Hospital, Beijing 100853, China) [ABSTRACT] Objective: To investigate the status quo and the development trend of the utilization of oral hypoglycemic drugs in our hospital so as to improve rational drug use. Methods: The utilization of oral hypoglycemic drugs from 2007 to 2009 was analyzed in respect of consumption sum, DDDs and average daily cost. Results: The consumption sum of oral hypoglycemic drugs has increased over the three years. Acarbose, metformin and glimepiride ranked the top 3 in respect of consumption sum, and acarbose, metformin and gliquidone dominated the top 3 in respect of DDDs. Conclusion: The utilization of oral hypoglycemic drugs in our hospital was basically rational, and drugs with good effectiveness, safety and tolerability were widely used in clinic. [KEY WORDS] Hypoglycemic drug; DDDs; DDC; Analysis of drug use 糖尿病是一种由遗传和环境因素相互作用所致 《药品的解剖学治疗学化学分类索引及规定日剂量》 [4] [5] 的以慢性高血糖为主要特征，同时伴有脂肪和蛋白质 （ATCDDDs ） ，未收载的药物以《新编药物学》 代谢紊乱的一组代谢性疾病，已被列为继心脑血管疾 （第16 版）推荐的成人常规日剂量高限值而定。DDDs 病、癌症之后严重危害人类健康的第三大疾病[1] 。当 = 某药品的销售总量/ 该药物的DDD 值，其含义为以 今，糖尿病患者及患病率快速增长。据世界卫生组织