带偏场校正和邻域约束的快速MR脑组织分割新方法.pdfVIP

8 Vol.38 No. 8 2010 8 ACTA ELECTRONICA SINICA Aug. 2010 MR 李 伟, 陈武凡 ( , 510515) : ( PVE) ( INU) , ( MR) .(2D) ( 3D) MR (WM) ( GM) ( CSF) . C- ( FCM) , . , INU, (MRF) .MR , . . : ; ; ; ; : TP391 : A : (2010) 0817807 A New and Fast Segmentation Algorithm for MR Brain Images with Bias Field Correction and Neighborhood Constrains LI Wei, CHEN Wufan (Institute of MedicalInf ormation and Technology, School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515, China) Abstract: Accurate and automatic brain tissue segmentation of magnetic resonance ( MR) images is a challenging problem because of partial volume (PV) effects, intensity nonuniformity ( INU, also known as bias field) and noise. We present an efficient and accurate,fully automatic twodimensional ( 2D) and threedimensional ( 3D) algorithm for segmenting brain MR images into anatomical major tissue classes such as white matter ( WM) , gray matter ( GM) and cerebrospinal fluid ( SCF) . Our algorithm is formulated by proposing an objective function based on standard FCM algorithm with bias field correction and neighborhood con strain. In our algorithm, a parameterized model is adopted to express the INU and a neighbor constrain similar to Markov random field ( MRF) is proposed to express spatial consistency of brain tissue. Experimental results with both synthetic and real data are in cluded, as well as comparisons of the performance of our algorithm with that of other published methods.The validation of the algo rithm shows good accuracy and fast convergence. Key words: image segmentation; bias field co