恶性肿瘤患者全身骨显像与骨密度检查的临床研究分析.pdfVIP

中国骨质疏松杂志 　2008 年 2 月第 14 卷第 2 期 　Chin J Osteoporos ,February 2008 ,Vol 14 ,No2 123 ·临床研究 · 恶性肿瘤患者全身骨显像与骨密度 检查的临床研究分析 崔建和 　崔芹 　谭维琴 　李天智 　吴曼青 ( ) 中图分类号 : R73 　　文献标识码 : A 　　文章编号 : 2008 摘要 : 目的　研究恶性肿瘤患者骨转移和非骨转移的全身骨显像与骨密度检查的变化 。方法 　采用 双探头 SPECT 仪器对 288 例恶性肿瘤患者进行全身骨显像 , 同时采用定量超声骨密度仪进行骨密度 ( ) 检查 ,并与 1292 例正常人作对照 。结果 　骨转移瘤患者的骨密度 BMD 水平较正常健康人群显著下 ( ) ( ) 降 P 005 ,非转移瘤患者的BMD 水平较正常健康人群无显著意义 P 005 。结论 　恶性肿瘤患 者在骨转移同时伴有骨质疏松 。 关键词 : 恶性肿瘤 ; 全身骨显像 ; 骨转移 ; 骨密度 Clinical research on the variance of whole body bone scan and bone mineral density with malignant carcinoma 　CUI Jianhe , CUI Qin , TAN Weiqin , et al . Department of Nuclear , the Affiliated Huaian First Hospital of Nanjing Medical University , Huaian 　223300 ,China Abstract : Objective 　To investigate the variance of Whole body bone scan and bone mineral density (BMD) in carcinoma patients with bone metastasis and non bone metastasis. Methods 　Double detectors SOECT was employed to detect the Whole body bone scan of 283 case malignant carcinoma and bone mass quantitative ultrasound was employed to detect the bone mass. And 1292 cases of healthy people was assayed by BMD. Results 　In carcinoma patients with metastasis group BMD decreased significantly ( P 005) . It was no difference( P ) 005 in the non metastasis group BMD. Conclusions 　The BMD contents in patients with malignancies significantly decrease compared with those healthy people. Key words : Malignancies ; Whole body bone scan ; Bone metastasis ; Bone mineral density 　　恶性肿瘤患者最终发生骨转移的几率较高 ,据