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医药导报2010年12月第29卷第12期卷终 ·1651· study[J]. JAlzheimers Dis,2007,13(1):97-107. randomized,controlled trial of memantine in patients with [11]摇 PORSTEINSSON A P,GROSSBERG GP,MINTZERJ,et moderate鄄to鄄severe Alzheimers disease[J]. Alzheimer Dis al.Memantine treatment in patients with mild to moderate Assoc Disord,2007,21 (2):136-143. Alzheimer s disease already receiving a cholinesterase [13]摇 JEFFREY L C,EUGENE S,PIERRE N T,et al. Beha鄄 inhibitor:a randomized, doubleblind, placebo鄄controlled v