2010 病毒学方法杂志.pdfVIP

This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and sharing with colleagues. Other uses, including reproduction and distribution, or selling or licensing copies, or posting to personal, institutional or third party websites are prohibited. In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier’s archiving and manuscript policies are encouraged to visit: /copyright Authors personal copy Journal of Virological Methods 165 (2010) 127–132 Contents lists available at ScienceDirect Journal of Virological Methods jo u rn al h o m e p a g e : w ww.el s ev i er.co m/ l o c a t e/ j v i r o m e t Effective inhibition of replication of infectious bursal disease virus by miRNAs delivered by vectors and targeting the VP2 gene Yongjuan Wang, Huaichang Sun ∗ , Pengpeng Shen, Xinyu Zhang, Xiaoli Xia, Bing Xia College of Veterinary Medicine, Yangzhou University, Jiangsu 225009, China a b s t r a c t Article history: RNA interference (RNAi) is a potent mechanism against a variety of viral infections. Infectious bursal Received 20 October 2008 disease virus (IBDV) causes an important disease economically in chickens, which is difficult t