复方泥鳅粉对小鼠高温及低温缺氧耐受性的影响.pdfVIP

Journal of Medi al S ien e Yanbian University De . 2007 Vol. 30 No. 4 # 250 # 1 2 张红英 , 金哲洙 ( 1. 延边大学基础医学院机能学实验中心; 2. 延边大学 医学学报编辑部: 吉林 延吉 133000) [ ] [ ] 探讨复方泥鳅粉 小鼠在高温及低温条件下耐缺氧能力. [ ] 灌胃给予小鼠不同 剂量的复方泥鳅粉(400, 800 mg/ kg) , 连续10 d, 末次给药1 h 后, 进行耐高低温实验. [ ] 复方泥鳅 粉大小剂量组小鼠在高低温及缺氧条件下存活时间均较 照组延长. [ ] 复方泥鳅粉可提高高温 及低温条件下小鼠的耐缺氧能力, 且呈量效关系. [ ] 缺氧; 低温; 高温; 小鼠 [ ] R 2851 5 [ ] A [ ] 1000- 1824( 2007) 04-0250-0 1 Influence of compound loach powder to hypoxia tolerance function under high and low temperature condition in mice 1 2 ZHANG Hong-ying , JIN Zhe-zhu ( 1. Function Exp eriment Center, Yanbian University College of Basic M edicine; 2. Editorial Board of ournal of Medical Science Yanbian Univ ersity : Yanj i 133000, ilin, China) ABS RAC : OBJ ECTI VE To dis uss the influen e of the ompound loa h pow der to hypox ia toleran e fun tion under high and low temperature in mi e. METH ODS ? The different dosage ( 400 mg/ kg 800 mg/ kg) of the ompound loa h pow der was performed by intragastri administration for ontinuous 10 days, and after 1 hour of administration, the high and low temperature experiment w as arried out . RES UL TS The ompound loa h pow der ould obviously lengthen the mi e to bear the high and low temperature hypoxia survival time. CON CL USI ON The ompound loa h pow der an enhan e hypoxia toleran e degree under the high and low temperature, and has dose effe t relationship. Key words:anox ia; hypothermia; hyperthermia; mi e HH-501 . 56, . , , . [ 1] A . 2 , 211 , . [ 2] 30, 3 , , . ( 400 mg/ kg) ,