替米沙坦、单硝酸异山梨酯联合治疗肺心病心衰60例临床疗效观察.docVIP

替米沙坦、单硝酸异山梨酯联合治疗肺心病心衰60例临床疗效观察 马孝忠 肖春泽 甘肃·临夏回族自治州人民医院呼吸科 【摘　要】　目的　观察替米沙坦、单硝酸异山梨酯（ISMN）联合治疗重症肺心病心衰的疗效。方法　60例肺心病心衰病人随机分为甲乙两组。甲组(治疗组)在常规治疗基础上应用替米沙坦、单硝酸异山梨酯, 5天为1个疗程。乙组(对照组)不应用替米沙坦、单硝酸异山梨酯,其余治疗同甲组。结果　甲组全血粘度,血浆粘度,红细胞压积(HCT)明显下降,在治疗前后相比有明显差异P0. 01;而乙组在治疗前后仅有HCT的变化差异P0. 05;甲乙两组治疗效果有显著差异P001。治疗组显效率74.3%,总有效率为92.7%;对照组显效率为46.6%,总有效率为68.3%,治疗后二组疗效对比,显效率差异有统计学意义(P0.01),总有效率差异有统计学意义(P0.01)，结论　替米沙坦、单硝酸异山梨酯（ISMN）合用治疗老年慢性肺源性心脏病心力衰竭的疗效显著,不良反应少,药物使用安全。 【关键词】　替米沙坦 单硝酸异山梨酯　肺心病心衰 60 cases of Clinical observation of Telmisartan and isosorbidemononitrate injection joint treatment on intensive pulmonary heart disease and heart failure Ma Xiaozhong Xiao Chunze Respiratory department of Linxia Hui minority prefecture hospital, Gan su Province 731100,China 【Abstract】　Objective: 60cases of clinical observevation of Telmisarton and isosorbidemononitrate injection joint treatment on intensive pulmonary heart disease and heart failure. Method :60 patients suffering from intensive pulmonary heart disease and heart failure were divided into observe group and control group randomly,patients observe group were on the basis of the routine treatment given Telmisartan and isosorbidemononitrate injection in 5 days period of treatment , while the coutrols received only routine treatment.clinical effect of the two groups was observed and compared.. Result : in observe group the whole blood viscosity ,plasma viscosity, HCT decline obviously ,obvious rate was 74.3% and tolal effective rate was 92.7% which in control group were 46.6% and 68.3%,respectively .There were significant diffevence in obvious rate and effective rates between the two groups(p0.01). Conclusion: The effect of Telmisartan and isosorbidemononitrate injection joint treatment on intensive pulmonary heart disease and heart failure is excellent with less side-effects and safe medicament. 【Key words】　Pulmonary heart disease; heart failure; Telmisartan, Isosorbidemononitrate