36例胃间质瘤临床病理学分析.pdf

·510· 2Q：巡Q：5 36例胃间质瘤临床病理学分析 章建国 施公胜池鸣鸣 黄华 【摘要】 瘤中的表达．结果很低度、低度、中度及高度侵袭危险性病例数分别为4例、18例、10例及4例；免疫组织化学显示很低、低度、中 中、高度侵袭危险病例。结论 胃GISTs临床病理的分级及Ki一67标记指数的测定有助于临床预后的判断。 【关键词】 胃间质瘤；免疫组织化学；CDll7蛋白；Ki一67蛋白 中图分类号：R735．2文献标识码：A 文章编号：1001—5930{2005)05—0510—04 ofGastrointestinalStromalTumor：a of36Cases ClinicopathologicalStudy Report ZHANG mi— Jian—guo，SHlGong—sheng，CHIMing-ming，eta1．DepartmentofPathology，A所liatedHospitalofNantong versity，Nantong，22600l the of featuresand ofGastrointestinalstromaltu— To correlation 【Abstract】0bjectiveinvestigate clinicopathologicprognosis The featuresanddatacollectedthe visitof36casesofGISTswereret— mours(GISTs)．Methods clinicopathologic duringfollow—up reviewed．Theantibodiesof andKi一67weredetected rospectively CDll7，CD34，SMA，S一100 by suits to Fletcher’S casesweresubdividedintothoseof lowriskof the scheme，the very infiltration(4cases)，lowrisk(18 According Ki一67 lowrisk，lowrisk，mediumriskand cases)，mediumrisk(10cases)andhighrisk(4cases)．Thelabelingindex(KLI)invery risk ofGISTs a high groups differencebetweenfour differencewasobservedinothermarkers．Atthe of28 groups(P0．01)．Nosignificant follow—upvisit，6 had riskand riskofinfiltration．ConclusionThe casesunderwentandmetastasis．Allthesixcasesmedium relapse high andKi一67 indexofGISTsbeusefulfor logicgrade labeling ma